Locomotor Recovery and Compensation Post-stroke (LRC)

Launched by INDIANA UNIVERSITY · Oct 5, 2021

Keywords

ClinConnect Summary

The Locomotor Recovery and Compensation Post-stroke (LRC) trial is studying how people recover and adapt their walking abilities after experiencing a stroke. Researchers want to understand the timeline of recovery during the weeks and months after a stroke and see if specific treatments can help improve this recovery, both early on and later. The goal is to develop better predictions about how different patients might regain their abilities and what strategies can help them the most.

To join the study, participants need to be adults aged 65 to 74 who have had their first stroke and are in a rehabilitation program. They should be able to follow simple instructions and have medical approval from their doctor to participate. It's important to note that those with serious heart, lung, or diabetes issues that could affect their ability to exercise, or those with other health conditions that limited their walking before the stroke, won't be eligible. Participants can expect to engage in assessments and possibly new interventions to help enhance their recovery. This research could lead to new insights and strategies to support stroke recovery in the future.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • individuals early post-stroke (\<15-30 days)
• • first ever stroke
• • unilateral hemiparesis
• • currently receiving inpatient rehabilitation
• • ability to follow 1-step commands
• • provision of informed consent
• • medical clearance from the rehabilitation physician to participate. \\
• Exclusion criteria:
• • uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure \> 200/110 mmHg, uncontrolled diabetes, end-stage renal disease)
• • absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines .
• • other orthopedic or neurological disorder that limited walking prior to stroke