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Search / Trial NCT05085171

An Enhanced Package of Care to Reduce Reduce Mortality in Advanced HIV Disease

Launched by MAKERERE UNIVERSITY · Oct 8, 2021

Trial Information

Current as of July 04, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is called "An Enhanced Package of Care to Reduce Mortality in Advanced HIV Disease." It aims to find out if a special care program can help people with advanced HIV live longer and stay engaged in their treatment. The study will use a method called point of care CD4 testing, which helps measure the strength of the immune system, combined with additional screenings and preventive treatments for infections that can occur in people with weakened immune systems.

To participate in this trial, you need to be over 18 years old, have a CD4 count of less than 200 cells per microliter (which indicates advanced HIV), and be willing to give consent for the enhanced care program. Unfortunately, if you have a controlled viral load (meaning your HIV is well-managed) or cannot regularly attend clinic visits, you won’t be eligible. If you join, you can expect regular visits for testing and care, and you’ll be part of an effort to improve health outcomes for those with advanced HIV disease.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>18 years
  • CD4\<200 cells/µL
  • Ability and willingness to give informed consent for the enhanced package of care arm.
  • Exclusion Criteria:
  • Known virologic suppression (viral load \<1000 copies/mL) within prior 3 months
  • Cannot or unlikely to attend regular clinic visits

About Makerere University

Makerere University, located in Kampala, Uganda, is a leading institution of higher learning and research that plays a pivotal role in advancing health sciences and clinical research in Africa. With a strong commitment to improving public health outcomes, the university engages in a wide range of clinical trials and health-related studies, focusing on addressing pressing health challenges in the region. Makerere University collaborates with various local and international partners to enhance research capacity, promote innovative solutions, and contribute to evidence-based healthcare practices, ultimately aiming to improve the quality of life for communities both locally and globally.

Locations

Kampala, , Uganda

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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