Cognition and QoL After Thyroid Surgery
Launched by KAROLINSKA UNIVERSITY HOSPITAL · Oct 11, 2021
Trial Information
Current as of September 11, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how thyroid surgery might affect thinking skills and quality of life in people who have thyroid nodules or thyroid cancer. Researchers want to understand if there are changes in cognitive function after surgery, how these changes relate to thyroid hormone levels, and how they affect patients' overall well-being. Participants will complete online tests to assess their cognitive abilities and fill out questionnaires about their quality of life, physical activity, and any other health concerns. They will also have blood tests to check hormone levels and inflammation.
To be eligible for the study, participants must be over 18 years old, have a thyroid nodule that needs surgery, and be able to read and understand Swedish. They should also have access to a computer with internet. However, individuals with certain previous health conditions, such as autoimmune hypothyroidism or other types of cancer, cannot participate. Those who join the study can expect to contribute valuable information that may help improve understanding of the long-term effects of thyroid surgery on cognitive health and quality of life.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age \>18 years old, indication for surgery because of a thyroid nodule Bethesda IV-VI
- • Able to read and understand the Swedish language
- • Access to desktop computer or laptop with internet connection
- • Able and willing to provide written informed consent
- Exclusion Criteria:
- • A previous diagnosis of (auto-immune) hypothyroidism
- • A previous cancer diagnosis (excluding basal cell cancer of the skin)
- • Indications for surgery other than (solely) a thyroid nodule (i.e., concomitant Graves)
- • A diagnosis of medullary and anaplastic thyroid cancer
About Karolinska University Hospital
Karolinska University Hospital is a leading academic medical center in Sweden, renowned for its commitment to advanced healthcare research and innovative clinical practices. As a key sponsor of clinical trials, the hospital leverages its extensive expertise in medical research and collaboration with Karolinska Institutet, one of the world's foremost medical universities. The institution is dedicated to enhancing patient care through rigorous scientific investigation, focusing on a wide range of therapeutic areas. With a multidisciplinary approach and a strong emphasis on translational medicine, Karolinska University Hospital aims to bridge the gap between laboratory findings and clinical application, ultimately striving to improve health outcomes and advance medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stockholm, Sweden
Patients applied
Trial Officials
Renske Altena, MD PhD
Principal Investigator
Karolinska Institutet
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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