Neural Mechanisms for Reducing Interference During Episodic Memory Formation

Launched by UNIVERSITY OF OREGON · Oct 11, 2021

Keywords

ClinConnect Summary

Objective: The goal of the research studies is to understand how memories are formed for similar experiences such that interference (confusion) between these memories is minimized. Of particular interest is the role of the hippocampus (a brain region important for memory).

Participants: Healthy individuals from the University of Oregon and surrounding community will be recruited through fliers, emails, and advertisements. For some of the studies, individuals between 18-80 years of age will be recruited. For others, individuals between 18-35 will be recruited.

Design: All studies will invo...

Gender

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Eligibility criteria

• Inclusion Criteria:
• Participants in behavioral studies must be:
• • healthy and between the ages of 18-35 years old
• • native English speakers
• • right-handed.
• Participants in fMRI studies must be:
• • healthy and between the ages of 18-80 years old
• • native English speakers
• • right-handed.
• Exclusion Criteria:
• For behavioral studies:
• • - Potential participants will be informed that use of psychoactive drugs, mental health disorders, and chronic or temporary sleep deficits (an average of less than 6 hours of sleep over the past month or less than 4 hours of sleep the night prior to the experimental session) are reasons for exclusion because of the potential influence on cognitive functioning.
• For fMRI studies:
• • For some sub-studies, individuals older than age 35 will be excluded because of potential differences in cognitive and brain function across age groups that are beyond the scope of the proposed studies.
• • Individuals will be informed that use of psychoactive drugs, mental health disorders, and chronic or temporary sleep deficits (an average of less than 6 hours of sleep over the past month or less than 4 hours of sleep the night prior to the experimental session) are reasons for exclusion because of the potential influence on cognitive functioning.