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Search / Trial NCT05095376

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Launched by NRG ONCOLOGY · Oct 15, 2021

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying whether adding a chemotherapy drug called lomustine (Gleostine®) to the usual treatment of temozolomide and radiation therapy can help patients with newly diagnosed glioblastoma, a type of brain cancer. The goal is to see if this combination can shrink or stabilize the tumor more effectively than using temozolomide and radiation therapy alone. Chemotherapy drugs like lomustine and temozolomide work by killing cancer cells or stopping them from growing, while radiation therapy uses high-energy rays to target and destroy the tumor.

To be eligible for this trial, participants must be between 18 and 70 years old, have a confirmed diagnosis of glioblastoma or gliosarcoma, and show specific genetic markers in their tumor. They should also be in reasonably good health overall. Participants can expect to receive treatment and regular check-ups to monitor their progress. It’s important to know that this study is currently recruiting, so interested patients should discuss it with their healthcare provider to see if they qualify.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • STEP 1 REGISTRATION: No known IDH mutation. (If tested before step 1 registration, patients known to have IDH mutation in the tumor on local or other testing are ineligible and should not be registered)
  • STEP 1 REGISTRATION: Availability of formalin-fixed paraffin-embedded (FFPE) tumor tissue block and hematoxylin and eosin (H\&E) stained slide to be sent for central pathology review for confirmation of histology and MGMT promoter methylation status. Note that tissue for central pathology review and central MGMT assessment must be received by the New York University (NYU) Center for Biospecimen Research and Development (CBRD) on or before postoperative calendar day 30. If tissue cannot be received by postoperative calendar day 30, then patients may NOT enroll on this trial as central pathology review will not be complete in time for the patient to start treatment no later than 8 weeks following surgery. Results of central pathology review and central MGMT analysis will generally be completed within 10 business days of receipt of tissue. Results will be entered by the central lab directly into Rave. Note: In the event of an additional tumor resection(s), tissue must be received within 30 days of the most recent resection and the latest resection must have been performed within 30 days after the initial resection. Surgical resection is required; stereotactic biopsy alone is not allowed because it will not provide sufficient tissue for MGMT analysis
  • STEP 1 REGISTRATION: Willing to use highly effective method of contraception for participants of childbearing potential (participants who may become pregnant or who may impregnate a partner) during therapy and for 6 months after completing treatment; this inclusion is necessary because the treatment in this study may be significantly teratogenic
  • STEP 1 REGISTRATION: The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information
  • STEP 2 REGISTRATION: Histopathologically proven diagnosis of glioblastoma (or gliosarcoma as a subtype of glioblastoma) confirmed by central pathology review
  • STEP 2 REGISTRATION: MGMT promoter with methylation confirmed by central pathology review. Note: Patients with tissue that is insufficient or inadequate for analysis, fails MGMT testing, or has indeterminate or unmethylated MGMT promoter are excluded
  • Note: Any MGMT result other than methylated would require step 2 registration to be reported as a "central review failure"
  • STEP 2 REGISTRATION: Contrast-enhanced brain MRI performed either after surgery or prior to step 2 registration
  • STEP 2 REGISTRATION: IDH mutation testing by at least one method (such as immunohistochemistry for IDH1 R132H) must be performed as part of standard of care and no mutation must be found (i.e IDH wildtype). (If a mutation is identified then the patient will be ineligible and must be registered as ineligible at step 2.)
  • STEP 2 REGISTRATION: History/physical examination within 28 days prior to step 2 registration
  • STEP 2 REGISTRATION: Karnofsky performance status (KPS) \>= 70 within 28 days prior to step 2 registration
  • STEP 2 REGISTRATION: Neurologic function assessment within 28 days prior to step 2 registration
  • STEP 2 REGISTRATION: Age 18-70 years
  • STEP 2 REGISTRATION: Hemoglobin \>= 10 g/dl (Note: the use of transfusion or other intervention to achieve hemoglobin \[Hgb\] \>= 10.0 g/dl is acceptable) (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Leukocytes \>= 2,000/mm\^3 (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Absolute neutrophil count \>= 1,500/mm\^3 (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Platelets \>= 100,000/mm\^3 (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Total bilirubin =\< 1.5 x institutional/lab upper limit of normal (ULN) (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase \[SGOT\]) =\< 2.5 x ULN (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 2.5 x ULN (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: Serum creatinine =\< 1.5 x ULN OR creatinine clearance (CrCl) \>= 50 mL/min (if using the Cockcroft-Gault formula) (Within 14 days prior to step 2 registration)
  • STEP 2 REGISTRATION: For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated
  • Note: Known positive test for hepatitis B virus surface antigen (HBV sAg) indicating acute or chronic infection would make the patient ineligible unless the viral load becomes undetectable on suppressive therapy. Patients who are immune to hepatitis B (anti-hepatitis B surface antibody positive) are eligible (e.g. patients immunized against hepatitis B)
  • STEP 2 REGISTRATION: For patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load
  • Note: Known positive test for hepatitis C virus ribonucleic acid (HCV ribonucleic acid \[RNA\]) indicating acute or chronic infection would make the patient ineligible unless the viral load becomes undetectable on suppressive therapy
  • STEP 2 REGISTRATION: Known human immunodeficiency virus (HIV) infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months prior to step 2 registration are eligible for this trial. Testing is not required for entry into protocol
  • STEP 2 REGISTRATION: Negative serum or urine pregnancy test (in persons of childbearing potential) within 14 days prior to step 2 registration
  • Childbearing potential is defined as any person who has experienced menarche and who has not undergone surgical sterilization (hysterectomy or bilateral oophorectomy) or who is not postmenopausal
  • Exclusion Criteria:
  • STEP 2 REGISTRATION: Prior therapy for tumor except for resection or prior laser interstitial thermal therapy (LITT). For example, prior chemotherapy, immunotherapy, or targeted therapy for GBM or lower grade glioma is disallowed (including but not limited to temozolomide, lomustine, bevacizumab, any viral therapy, ipilimumab or other CTLA-4 antibody, PD-1 antibody, CD-137 agonist, CD40 antibody, PDL-1 or 2 antibody, vaccine therapy, polio or similar viral injection as treatment for the tumor, and/or any other antibody or drug specifically targeting T-cell co-stimulation or immune checkpoint pathways) as is Gliadel wafer, radiotherapy, radiosurgery, vaccine or other immunotherapy, brachytherapy, or convection enhanced delivery
  • Note: 5-aminolevulinic acid (ALA)-mediated fluorescent guided resection (FGR) photodynamic therapy (PDT) or fluorescein administered prior to/during surgery to aid resection is not exclusionary and is not considered a chemotherapy or intracerebral agent. Prior laser interstitial thermal therapy (LITT) is allowed
  • STEP 2 REGISTRATION: Current or planned treatment with any other investigational agents for the study cancer
  • STEP 2 REGISTRATION: Definitive clinical or radiologic evidence of metastatic disease outside the brain
  • STEP 2 REGISTRATION: Prior invasive malignancy (except non-melanomatous skin cancer, cervical cancer in situ and melanoma in situ) unless disease free for a minimum of 2 years
  • STEP 2 REGISTRATION: Prior radiotherapy to the head or neck that would result in overlap of radiation therapy fields
  • STEP 2 REGISTRATION: Pregnancy and individuals unwilling to discontinue nursing due to the potential teratogenic effects and potential risk for adverse events in nursing infants
  • STEP 2 REGISTRATION: History of allergic reactions attributed to compounds of similar chemical or biologic composition to temozolomide or lomustine
  • STEP 2 REGISTRATION: History of pulmonary fibrosis
  • * STEP 2 REGISTRATION: Uncontrolled intercurrent illness including, but not limited to:
  • Ongoing or active infection requiring intravenous (IV) antibiotics, IV antiviral, or IV antifungal treatment
  • Symptomatic congestive heart failure, defined as New York Heart Association Functional Classification III/IV (Note: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification)
  • Unstable angina pectoris within 6 months prior to Step 2 registration
  • Uncontrolled cardiac arrhythmia
  • Psychiatric illness/social situations that would limit compliance with study requirements
  • STEP 2 REGISTRATION: No evidence of diffuse leptomeningeal disease that requires whole brain irradiation

About Nrg Oncology

NRG Oncology is a prominent clinical trial sponsor dedicated to advancing cancer research through innovative multi-institutional studies. Comprising a collaborative network of leading academic institutions and community hospitals, NRG Oncology focuses on enhancing patient outcomes by conducting rigorous clinical trials that evaluate new treatment strategies and improve existing therapies. With a commitment to scientific excellence and patient-centered care, the organization plays a vital role in shaping the future of oncology by integrating cutting-edge research with clinical practice, ultimately striving to translate findings into meaningful improvements in cancer care.

Locations

Lebanon, New Hampshire, United States

Cleveland, Ohio, United States

Saint Louis, Missouri, United States

Kalamazoo, Michigan, United States

Burnsville, Minnesota, United States

Edina, Minnesota, United States

Waconia, Minnesota, United States

Sioux Falls, South Dakota, United States

Toms River, New Jersey, United States

Salt Lake City, Utah, United States

Little Rock, Arkansas, United States

Oklahoma City, Oklahoma, United States

Duarte, California, United States

La Crosse, Wisconsin, United States

Long Branch, New Jersey, United States

Cleveland, Ohio, United States

Saint Paul, Minnesota, United States

Kalamazoo, Michigan, United States

Logan, Utah, United States

Ogden, Utah, United States

Cincinnati, Ohio, United States

Dallas, Texas, United States

Fort Collins, Colorado, United States

Sioux City, Iowa, United States

Chillicothe, Ohio, United States

Gresham, Oregon, United States

Tualatin, Oregon, United States

Coon Rapids, Minnesota, United States

Urbana, Illinois, United States

Ann Arbor, Michigan, United States

Minneapolis, Minnesota, United States

Saint Paul, Minnesota, United States

Dayton, Ohio, United States

Rapid City, South Dakota, United States

Effingham, Illinois, United States

Kansas City, Missouri, United States

Greenville, Ohio, United States

Johnson Creek, Wisconsin, United States

Fayetteville, Arkansas, United States

Springfield, Illinois, United States

Houston, Texas, United States

Fairfax, Virginia, United States

Downers Grove, Illinois, United States

Roseville, California, United States

Hazel Crest, Illinois, United States

Springfield, Illinois, United States

Englewood, New Jersey, United States

Pittsburgh, Pennsylvania, United States

Minneapolis, Minnesota, United States

Rochester, New York, United States

Danville, Pennsylvania, United States

Salt Lake City, Utah, United States

Orange, California, United States

Atlanta, Georgia, United States

Savannah, Georgia, United States

Chicago, Illinois, United States

Chicago, Illinois, United States

Baltimore, Maryland, United States

Duluth, Minnesota, United States

Saint Cloud, Minnesota, United States

Saint Louis, Missouri, United States

New Brunswick, New Jersey, United States

New York, New York, United States

Chapel Hill, North Carolina, United States

Bismarck, North Dakota, United States

Fargo, North Dakota, United States

Columbus, Ohio, United States

Hershey, Pennsylvania, United States

Pittsburgh, Pennsylvania, United States

Charleston, South Carolina, United States

Burlington, Vermont, United States

Seattle, Washington, United States

Aurora, Illinois, United States

Lexington, Kentucky, United States

Neptune, New Jersey, United States

Columbus, Ohio, United States

Kettering, Ohio, United States

Tulsa, Oklahoma, United States

Allentown, Pennsylvania, United States

Morgantown, West Virginia, United States

Provo, Utah, United States

Wyoming, Michigan, United States

Cape Girardeau, Missouri, United States

Fridley, Minnesota, United States

Robbinsdale, Minnesota, United States

Saint Louis Park, Minnesota, United States

Livingston, New Jersey, United States

Berlin, Vermont, United States

Louisville, Kentucky, United States

Milwaukee, Wisconsin, United States

Grand Rapids, Michigan, United States

Oak Lawn, Illinois, United States

Oakland, California, United States

Park Ridge, Illinois, United States

Albuquerque, New Mexico, United States

Sioux Falls, South Dakota, United States

Dallas, Texas, United States

Houston, Texas, United States

Richmond, Virginia, United States

Sacramento, California, United States

Miami, Florida, United States

Augusta, Georgia, United States

Detroit, Michigan, United States

Saint Louis, Missouri, United States

Toledo, Ohio, United States

Green Bay, Wisconsin, United States

Madison, Wisconsin, United States

Portland, Oregon, United States

Decatur, Illinois, United States

Ottawa, Illinois, United States

Peoria, Illinois, United States

Peoria, Illinois, United States

Cedar Rapids, Iowa, United States

Cedar Rapids, Iowa, United States

Clive, Iowa, United States

Des Moines, Iowa, United States

Warren, Michigan, United States

Brainerd, Minnesota, United States

Duluth, Minnesota, United States

Duluth, Minnesota, United States

Pontiac, Michigan, United States

Maplewood, Minnesota, United States

Maplewood, Minnesota, United States

Stillwater, Minnesota, United States

Wilkes Barre, Pennsylvania, United States

Kalamazoo, Michigan, United States

Alexandria, Virginia, United States

Rohnert Park, California, United States

Sacramento, California, United States

Canandaigua, New York, United States

Concord, California, United States

Fremont, California, United States

Los Angeles, California, United States

Richmond, California, United States

Roseville, California, United States

Sacramento, California, United States

San Francisco, California, United States

San Jose, California, United States

San Leandro, California, United States

Santa Clara, California, United States

Santa Rosa, California, United States

South San Francisco, California, United States

Stockton, California, United States

Vallejo, California, United States

Walnut Creek, California, United States

Walnut Creek, California, United States

Galesburg, Illinois, United States

Ames, Iowa, United States

Kansas City, Kansas, United States

Wichita, Kansas, United States

Grand Rapids, Michigan, United States

Grand Rapids, Michigan, United States

Saginaw, Michigan, United States

Bemidji, Minnesota, United States

Springfield, Missouri, United States

Billings, Montana, United States

Reno, Nevada, United States

Newark, New Jersey, United States

Akron, Ohio, United States

Cincinnati, Ohio, United States

Dayton, Ohio, United States

Franklin, Ohio, United States

Sylvania, Ohio, United States

Troy, Ohio, United States

Portland, Oregon, United States

Portland, Oregon, United States

West Reading, Pennsylvania, United States

Sioux Falls, South Dakota, United States

American Fork, Utah, United States

Cedar City, Utah, United States

Murray, Utah, United States

Burlington, Vermont, United States

Richmond, Virginia, United States

Oconomowoc, Wisconsin, United States

Rhinelander, Wisconsin, United States

Sheboygan, Wisconsin, United States

Stevens Point, Wisconsin, United States

West Allis, Wisconsin, United States

Berkeley, California, United States

Mountain View, California, United States

Palo Alto, California, United States

San Francisco, California, United States

Jacksonville, Florida, United States

Antigo, Wisconsin, United States

Wausau, Wisconsin, United States

Libertyville, Illinois, United States

Livonia, Michigan, United States

Newberg, Oregon, United States

Oshkosh, Wisconsin, United States

Munster, Indiana, United States

Littleton, Colorado, United States

Albuquerque, New Mexico, United States

Boise, Idaho, United States

Elgin, Illinois, United States

Canton, Illinois, United States

Carthage, Illinois, United States

Eureka, Illinois, United States

Kewanee, Illinois, United States

Macomb, Illinois, United States

Peru, Illinois, United States

Princeton, Illinois, United States

Parker, Colorado, United States

Lake Success, New York, United States

Grafton, Wisconsin, United States

Colorado Springs, Colorado, United States

Bloomington, Illinois, United States

Chicago, Illinois, United States

Pekin, Illinois, United States

Erie, Pennsylvania, United States

Saint George, Utah, United States

Burlington, Wisconsin, United States

Germantown, Wisconsin, United States

Green Bay, Wisconsin, United States

Kenosha, Wisconsin, United States

Marinette, Wisconsin, United States

Milwaukee, Wisconsin, United States

Racine, Wisconsin, United States

Summit, Wisconsin, United States

Two Rivers, Wisconsin, United States

Wauwatosa, Wisconsin, United States

Wisconsin Rapids, Wisconsin, United States

Houston, Texas, United States

Auburn, California, United States

Carmichael, California, United States

Roseville, California, United States

Saint Johnsbury, Vermont, United States

Santa Rosa, California, United States

Fairbanks, Alaska, United States

Vacaville, California, United States

Indianapolis, Indiana, United States

Indianapolis, Indiana, United States

Saint Louis, Missouri, United States

Montreal, Quebec, Canada

Montreal, Quebec, Canada

Anaheim, California, United States

Antioch, California, United States

Bellflower, California, United States

Fresno, California, United States

Modesto, California, United States

Oakland, California, United States

Rancho Cordova, California, United States

Roseville, California, United States

San Diego, California, United States

South San Francisco, California, United States

Sunnyvale, California, United States

Atlanta, Georgia, United States

Fruitland, Idaho, United States

Meridian, Idaho, United States

Twin Falls, Idaho, United States

Overland Park, Kansas, United States

Kansas City, Missouri, United States

Lee's Summit, Missouri, United States

Fargo, North Dakota, United States

Monroeville, Pennsylvania, United States

Vancouver, Washington, United States

New Richmond, Wisconsin, United States

Urbana, Illinois, United States

Rogers, Arkansas, United States

Springfield, Illinois, United States

Saint Peters, Missouri, United States

Greensburg, Pennsylvania, United States

Johnstown, Pennsylvania, United States

Pittsburgh, Pennsylvania, United States

Pittsburgh, Pennsylvania, United States

Fairfax, Virginia, United States

Loveland, Colorado, United States

Auburn, California, United States

Clive, Iowa, United States

West Des Moines, Iowa, United States

Brighton, Michigan, United States

Canton, Michigan, United States

Caro, Michigan, United States

Chelsea, Michigan, United States

Grosse Pointe Woods, Michigan, United States

Macomb, Michigan, United States

Marlette, Michigan, United States

Pontiac, Michigan, United States

Saginaw, Michigan, United States

West Branch, Michigan, United States

Minneapolis, Minnesota, United States

Centerville, Ohio, United States

Dublin, Ohio, United States

West Chester, Ohio, United States

Lewisburg, Pennsylvania, United States

Colorado Springs, Colorado, United States

Creston, Iowa, United States

Centralia, Illinois, United States

Danville, Illinois, United States

Decatur, Illinois, United States

Effingham, Illinois, United States

Mattoon, Illinois, United States

New Lenox, Illinois, United States

O'fallon, Illinois, United States

Louisville, Kentucky, United States

Brighton, Michigan, United States

Canton, Michigan, United States

Chelsea, Michigan, United States

Ypsilanti, Michigan, United States

Maple Grove, Minnesota, United States

Sainte Genevieve, Missouri, United States

Sullivan, Missouri, United States

Sunset Hills, Missouri, United States

Centerville, Ohio, United States

Dayton, Ohio, United States

Franklin, Ohio, United States

Greenville, Ohio, United States

Sturgeon Bay, Wisconsin, United States

Ames, Iowa, United States

Pottsville, Pennsylvania, United States

Richmond, Virginia, United States

Dublin, California, United States

Fresno, California, United States

Sacramento, California, United States

San Rafael, California, United States

Monticello, Minnesota, United States

Creve Coeur, Missouri, United States

Saint Louis, Missouri, United States

Riverton, Utah, United States

New Brunswick, New Jersey, United States

Indianapolis, Indiana, United States

Fremont, California, United States

Wexford, Pennsylvania, United States

Richmond, Virginia, United States

Milwaukee, Wisconsin, United States

Charleston, South Carolina, United States

Charleston, South Carolina, United States

Mukwonago, Wisconsin, United States

Waukesha, Wisconsin, United States

Ontario, California, United States

Des Moines, Iowa, United States

Overland Park, Kansas, United States

Westwood, Kansas, United States

Louisville, Kentucky, United States

Ashland, Wisconsin, United States

Columbia, Maryland, United States

Midlothian, Virginia, United States

Orland Park, Illinois, United States

Glen Burnie, Maryland, United States

North Kansas City, Missouri, United States

Jefferson Hills, Pennsylvania, United States

Elk Grove, California, United States

Rocklin, California, United States

Sacramento, California, United States

Woodland, California, United States

Tawas City, Michigan, United States

Brewer, Maine, United States

Beavercreek, Ohio, United States

Charleston, South Carolina, United States

Springdale, Arkansas, United States

Deer River, Minnesota, United States

Hibbing, Minnesota, United States

Sandstone, Minnesota, United States

Virginia, Minnesota, United States

Ashland, Wisconsin, United States

Colorado Springs, Colorado, United States

Jersey City, New Jersey, United States

Mechanicsville, Virginia, United States

Farrell, Pennsylvania, United States

Altoona, Pennsylvania, United States

Washington, Illinois, United States

Farmington, Missouri, United States

Redwood City, California, United States

Fort Collins, Colorado, United States

Greeley, Colorado, United States

Burnsville, Minnesota, United States

Richmond, Virginia, United States

Bozeman, Montana, United States

Golden, Colorado, United States

Carmichael, California, United States

Barrington, Illinois, United States

Crystal Lake, Illinois, United States

Crown Point, Indiana, United States

Dyer, Indiana, United States

Hobart, Indiana, United States

Hobart, Indiana, United States

Munster, Indiana, United States

Valparaiso, Indiana, United States

Vancouver, Washington, United States

Pierre, South Dakota, United States

Alton, Illinois, United States

Hayward, Wisconsin, United States

Spooner, Wisconsin, United States

Superior, Wisconsin, United States

Nampa, Idaho, United States

Springfield, Illinois, United States

Dansville, New York, United States

Shiloh, Illinois, United States

Sheboygan, Wisconsin, United States

Yankton, South Dakota, United States

Des Moines, Iowa, United States

Lebanon, New Hampshire, United States

Wyoming, Michigan, United States

Grand Rapids, Michigan, United States

Troy, Ohio, United States

Pontiac, Michigan, United States

Ann Arbor, Michigan, United States

Brighton, Michigan, United States

Chelsea, Michigan, United States

Dayton, Ohio, United States

Danville, Illinois, United States

Greenville, Ohio, United States

Ames, Iowa, United States

Canton, Michigan, United States

Rhinelander, Wisconsin, United States

Stevens Point, Wisconsin, United States

Ankeny, Iowa, United States

Sunset Hills, Missouri, United States

O'fallon, Illinois, United States

Des Moines, Iowa, United States

Clive, Iowa, United States

Lansing, Michigan, United States

Carmichael, California, United States

Grand Rapids, Michigan, United States

Concord, California, United States

Pontiac, Michigan, United States

Madison, Wisconsin, United States

Saint Johnsbury, Vermont, United States

Dayton, Ohio, United States

Dayton, Ohio, United States

Grand Rapids, Michigan, United States

Johnson Creek, Wisconsin, United States

Irvine, California, United States

Saginaw, Michigan, United States

Tawas City, Michigan, United States

Crown Point, Indiana, United States

Golden, Colorado, United States

Madison, Wisconsin, United States

Detroit, Michigan, United States

Aurora, Illinois, United States

Kalamazoo, Michigan, United States

Warren, Michigan, United States

Macomb, Michigan, United States

Grosse Pointe Woods, Michigan, United States

Ankeny, Iowa, United States

Clive, Iowa, United States

Des Moines, Iowa, United States

Des Moines, Iowa, United States

Waukee, Iowa, United States

Littleton, Colorado, United States

Parker, Colorado, United States

Patients applied

0 patients applied

Trial Officials

Fabio M Iwamoto

Principal Investigator

NRG Oncology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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