Chronic Heart Failure With Preserved Ejection Fraction - COngestion eValuation

Launched by CENTRAL HOSPITAL, NANCY, FRANCE · Oct 27, 2021

Keywords

ClinConnect Summary

The CHF-COV Preserved study is looking at how to better understand and identify congestion in patients with chronic heart failure, specifically for those whose heart still pumps well (this is known as preserved ejection fraction). Congestion is when fluid builds up in the body, causing symptoms that can lead to hospital visits. The goal of this trial is to find markers—like signs observed during a physical exam, blood test results, and ultrasound images—that can help predict the risk of serious health issues, such as hospitalization or needing strong medications.

To take part in this study, participants must be adults aged 18 or older who have been diagnosed with chronic heart failure and are hospitalized for a scheduled visit or consultation. They should have a preserved heart function, meaning their heart pumps normally. Participants will receive detailed information about the study and must agree to join by signing a consent form. Throughout the study, they can expect to undergo various evaluations to help the researchers gather information that could improve future care for heart failure patients. It's important to note that certain health conditions may prevent someone from participating, so eligibility is carefully assessed.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with chronic acute heart failure with preserved ejection fraction admitted in hospital for scheduled day hospitalization or consultation
• • Patient with preserved left ventricular ejection fraction (≥50%).
• • Age ≥18 years
• • Patients having received complete information regarding the study design and having signed their informed consent form.
• • Patient affiliated to or beneficiary of a social security scheme
• Exclusion Criteria:
• • Comorbidity for which the life expectancy is ≤ 3 months
• • Dialysis patient (peritoneal dialysis or hemodialysis) or patients with glomerular filtration rate \<15 ml/min/m2 at inclusion.
• • History of lobectomy or pneumonectomy lung surgery
• • Severe pulmonary or pleural pathology preventing reliable acquisition of lung ultrasound images: severe emphysema, chronic pleurisy, pulmonary fibrosis, etc.
• • Pregnant woman, parturient or nursing mother
• • Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
• • Adult person who is unable to give consent
• • Person deprived of liberty by a judicial or administrative decision,
• • Person subject to psychiatric care pursuant to Articles L. 3212-1 and L. 3213-1 of the Public Health Code.