Robotic Evaluations of Motor Learning During Stroke Neurorehabilitation

Launched by UNIVERSITY OF CALGARY · Nov 2, 2021

Keywords

ClinConnect Summary

The RELEARN trial is a research study designed to learn more about how stroke survivors recover their ability to move their arms and hands after a stroke. Specifically, it looks at how the brain helps with this recovery process in the early days after a stroke. The study is currently recruiting participants, including people who have had their first stroke affecting one side of the body and healthy individuals who don’t have any significant health issues. To be eligible, stroke participants need to be more than 18 years old, have some difficulty with their arm movement, and be about a week after their stroke. Healthy participants only need to be in good health and over 18 years old.

If you decide to participate in this study, you will undergo assessments to evaluate your movement abilities and help researchers understand how recovery happens. It’s important to know that participants with certain medical conditions, past strokes, or significant arm-related health issues may not qualify for the study. Your involvement could contribute valuable insights into stroke rehabilitation and help improve future treatments for individuals recovering from strokes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria for Stroke Participants:
• • First time, unilateral ischemic stroke in middle cerebral artery territory, motor and/or sensory tracts and confirmed by clinical examination (including neuroimaging)
• • 7±6 days post-stroke
• • Upper limb impairment
• • \>18 years old
• • Fugl-Meyer upper extremity score between 30 and 57
• • Vision better than 20/50 (corrected)
• • Able to follow 3-step task commands
• Inclusion Criteria for Control Participants:
• • \>18 years old
• • Good health
• Exclusion Criteria for Stroke Participants:
• * History of:
• • 1. past undiagnosed stroke (evident on neuroimaging),
• • 2. neglect (screened with Behavioral Inattention Test),
• • 3. apraxia, or
• • 4. upper extremity orthopedic or muscular issues
• • Secondary neurologic injury or disease (e.g., Parkinson's)
• • Contraindication to MRI
• • Medical or neuropsychiatric conditions that would interfere with study outcomes, or where participation presents a risk to the subject
• • Enrollment in an interventional trial that supplements standard therapy
• Exclusion Criteria for Control Participants:
• • • Significant upper limb neurologic or orthopedic conditions