Observation on Obesity Undergoing XOWI

Launched by FENG TAO · Nov 7, 2021

Keywords

ClinConnect Summary

Obesity is a worldwide problem to public health, with a prevalence rate of 12.4% according to recent studies. It is associated with a series of chronic non-communicable diseases, including type 2 diabetes, cardiovascular diseases, non-alcoholic fatty liver, polycystic ovary syndrome, cancer, and so on. Many publications reported Chinese herbal therapy as an effective anti- obesity management. However, there are still few observational studies on its effect in patients undergoing Chinese herbal therapy more than 6 months, or on its safety.

This is a mono-centric, prospective study conducted...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ·age ranged from 16-70 years old body mas index over 28kg/m2
• Exclusion Criteria:
• • secondary cause of obesity such as hypothalamic obesity, cushing syndrome, and hypophysis dysfunction, etc.
• • pregnancy or lactation
• • significant dysfunction of heart, liver, kidney and systemic organs (NYHA Class III or IV; alanine aminotransferase(ALT) and / or aspartate aminotransferase(AST) ≥ 5 times the normal upper limit; glomerular filtration rate\< 60(ml/min) or with malignant tumor
• • body weight fluctuated by more than 5 kg in the last 3 months with drug abuse or alcohol addiction
• • with serious mental and neurological disorders
• • blood pressure ≥ 180/110 mmHg, or malignant hypertension
• • organic and systemic diseases intolerant of herb