The PASTDUe Nutrition Ecosystem Project (PASTDUe)

Launched by DUKE UNIVERSITY · Nov 9, 2021

Keywords

ClinConnect Summary

The PASTDUe Nutrition Ecosystem Project is a research study that aims to find out if a new way of providing nutrition can help patients recover better after having abdominal surgery and needing special feeding in the intensive care unit (ICU). This study will focus on patients who cannot eat normally for more than 72 hours due to their condition. The researchers will use a structured plan that includes tube feeding, nutritional supplements, and special devices to measure how many calories each patient needs. They will also keep track of changes in fat and muscle mass during the hospital stay, ensuring that patients receive the right nutrition to support their recovery.

To be eligible for this study, participants must be at least 18 years old and have been admitted to the ICU due to serious abdominal issues or trauma. They cannot be expected to eat normally for more than three days after surgery. If you choose to participate, you can expect to have your nutrition closely monitored with non-invasive devices and regular check-ups throughout your hospital stay. This study is designed to be safe, with all methods used being approved for patient care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age \>= 18 years
• • 2. ICU admission with major abdominal trauma, intra-abdominal sepsis, ischemic bowel/vascular emergencies, or penetrating trauma
• • 3. Not expected to receive oral or enteral nutrition for \> 72 hours
• • 4. Primary team approval of PN
• • 4. \< 72 hours post-operative intervention
• Exclusion Criteria:
• • 1. Expected death or withdrawal of life-sustaining treatment within the first 72 hours of ICU admission
• • 2. Patients admitted with
• • Diabetic ketoacidosis or non-ketotic hyperosmolar coma
• • MELD \> 20 or acute fulminant hepatic failure
• • 3. Patients allergic to any component of parenteral nutrition or lipid solution
• • 4. Pregnant or breastfeeding patients
• • 5. Incarcerated or prisoner prior to admission