ClinConnect ClinConnect Logo
Search / Trial NCT05127889

the Remineralizing Self-Assembling Peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride White Spot Lesions

Launched by AIN SHAMS UNIVERSITY · Nov 9, 2021

Trial Information

Current as of August 02, 2025

Unknown status

Keywords

Wsls,

ClinConnect Summary

White spot lesions (WSLs), defined as "white opacity," occur as a result of subsurface enamel demineralization that is located on smooth surfaces of teeth. The reason of the white appearance is the changes in light-scattering optical properties of the decalcified enamel. The aim of the current study is to compare the remineralizing ability of Self-assembling peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride varnishes

A) Primary Objective

Assessment of:

* Dimensions of the WSLs through digital photography.
* The color of WSLs through spe...

Gender

ALL

Eligibility criteria

  • Inclusion criteria
  • Patients aged from 8 to 12 years old
  • Patients who are medically free from any diseases that would cause enamel defects.
  • Patients should have WSLs in labial surface of upper or lower permanent anterior teeth with a score of 1 \& 2 according to the ICDAS that don't require operative intervention.
  • Exclusion criteria
  • Patients receiving the following medications will be excluded from the study: tetracyclines, any other medication known to stain teeth, any medication causing dry mouth and/or xerostomia.
  • Uncooperative patients
  • Mouth breathers

About Ain Shams University

Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials