the Remineralizing Self-Assembling Peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride White Spot Lesions
Launched by AIN SHAMS UNIVERSITY · Nov 9, 2021
Trial Information
Current as of August 02, 2025
Unknown status
Keywords
ClinConnect Summary
White spot lesions (WSLs), defined as "white opacity," occur as a result of subsurface enamel demineralization that is located on smooth surfaces of teeth. The reason of the white appearance is the changes in light-scattering optical properties of the decalcified enamel. The aim of the current study is to compare the remineralizing ability of Self-assembling peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride varnishes
A) Primary Objective
Assessment of:
* Dimensions of the WSLs through digital photography.
* The color of WSLs through spe...
Gender
ALL
Eligibility criteria
- • Inclusion criteria
- • Patients aged from 8 to 12 years old
- • Patients who are medically free from any diseases that would cause enamel defects.
- • Patients should have WSLs in labial surface of upper or lower permanent anterior teeth with a score of 1 \& 2 according to the ICDAS that don't require operative intervention.
- • Exclusion criteria
- • Patients receiving the following medications will be excluded from the study: tetracyclines, any other medication known to stain teeth, any medication causing dry mouth and/or xerostomia.
- • Uncooperative patients
- • Mouth breathers
About Ain Shams University
Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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