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Search / Trial NCT05132543

Neural Basis of Cognition

Launched by DUKE UNIVERSITY · Nov 12, 2021

Trial Information

Current as of July 23, 2025

Not yet recruiting

Keywords

ClinConnect Summary

The clinical trial titled "Neural Basis of Cognition" aims to learn more about how epilepsy affects thinking and memory by studying patients who are undergoing treatment for epilepsy that does not respond to medications. Researchers will conduct experiments to explore how our brains process information, remember things, and understand language. They will also look closely at brain activity during sleep and when awake to better understand the connection between epilepsy and cognitive functions. The ultimate goal is to find ways to improve how we understand seizures and epilepsy in general, potentially leading to better treatments in the future.

To participate in this study, interested individuals should be between the ages of 12 and 18 and are likely to have surgery for epilepsy or other brain conditions. They should be fluent in English and not have any major cognitive impairments. Participants will use safe devices to monitor brain activity, and all information collected will be kept secure. This study is not yet recruiting participants, but it offers a chance to contribute to important research that could help others with epilepsy.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Potential subjects will come from adult and pediatric patients (between the ages of 12 and 18) undergoing surgery for the treatment of pharmacologically resistant epilepsy, brain tumor resection, brain mass resection, or deep brain stimulation (DBS) for the first time
  • Proficient English speakers
  • No Major cognitive impairment
  • Exclusion Criteria:
  • Previous DBS procedure
  • Subject unable to consent to study

About Duke University

Duke University, a leading academic and research institution located in Durham, North Carolina, is renowned for its commitment to advancing healthcare through innovative clinical research. With a strong emphasis on interdisciplinary collaboration, Duke conducts a wide array of clinical trials aimed at developing cutting-edge therapies and improving patient outcomes across various medical fields. The university's Clinical Research Institute provides comprehensive support for trial design, implementation, and regulatory compliance, ensuring that all research adheres to the highest ethical and scientific standards. Duke’s dedication to translating research findings into effective clinical practices underscores its role as a pivotal contributor to the global medical community.

Locations

Patients applied

0 patients applied

Trial Officials

Gregory B Cogan, PhD

Principal Investigator

Duke University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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