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Search / Trial NCT05134454

Atrial Fibrillation Screening Post Ischemic Cerebrovascular Events

Launched by KAROLINSKA INSTITUTET · Nov 19, 2021

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Stroke Tia Atrial Fibrillation Ecg Oral Anticoagulation

ClinConnect Summary

This clinical trial is studying the importance of checking for a heart condition called atrial fibrillation (AF) in older patients who have recently experienced a stroke or a mini-stroke (known as a Transient Ischemic Attack, or TIA). Atrial fibrillation can increase the risk of having another stroke. By detecting AF early, doctors can adjust treatment to help reduce this risk. The study will involve patients aged 70 and older who have been hospitalized for a stroke or TIA within the last two weeks.

Participants will be randomly assigned to one of two groups: one will receive a standard heart rhythm test lasting 1-2 days, while the other will undergo a more detailed test for 14 days, with monitoring done at least twice. If AF is found, participants will be offered a specific treatment to help prevent further strokes. This trial is important because it aims to improve screening guidelines for heart rhythm checks after a stroke, which could greatly benefit many patients facing a challenging recovery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients aged ≥ 70 years
  • A diagnosis of ischemic stroke or TIA within 14 days from inclusion.
  • Exclusion Criteria:
  • Previously diagnosed atrial fibrillation
  • Contraindication to oral anticoagulant treatment according to Summary of Product Characteristics.
  • Indication for anticoagulant treatment other than atrial fibrillation, e.g. venous thromboembolism or mechanical heart valve prosthesis
  • Dual antiplatelet therapy not interchangeable to oral anticoagulation
  • Patients with pacemaker, implantable cardioverter defibrillator or implantable cardiac monitor.
  • Patients who, according to the investigator, will not be able to comply with the study protocol.

About Karolinska Institutet

Karolinska Institutet is a renowned medical university located in Sweden, recognized for its commitment to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the institution focuses on translating scientific discoveries into effective treatments and therapies, emphasizing patient-centered approaches. With a strong emphasis on collaboration and interdisciplinary research, Karolinska Institutet plays a pivotal role in addressing global health challenges and improving patient outcomes, leveraging its extensive network of experts and state-of-the-art facilities to drive clinical advancements.

Locations

Stockholm, , Sweden

Patients applied

0 patients applied

Trial Officials

Johan Engdahl, MD, PhD

Study Chair

Karolinska Institutet

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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