Conservative Management for PAS Pilot

Launched by UNIVERSITY OF UTAH · Nov 17, 2021

Keywords

ClinConnect Summary

This clinical trial, called the Conservative Management for PAS Pilot, is exploring a different treatment option for women diagnosed with a serious pregnancy condition known as placenta accreta spectrum (PAS). Traditionally, many women with this condition are advised to have a hysterectomy, which is the surgical removal of the uterus. However, this study is looking at a less invasive approach called "conservative in situ management," which may be safer and more suitable for some patients. The goal of the trial is to gather important information that could help doctors and patients make better decisions about their care in the future.

To participate in this trial, women must be at least 18 years old, have a history of cesarean delivery along with certain conditions related to their placenta, and be planning to deliver between 34 and 36 weeks of pregnancy. Those who are eligible will be monitored closely during their pregnancy. The trial is currently recruiting participants, and it aims to provide valuable insights that could lead to more effective and cost-efficient care for women facing this challenging condition.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age 18 and older
• • History of cesarean delivery AND placenta previa OR anterior low-lying placenta AND suspected of having PAS on prenatal imaging (ultrasound/MRI)
• • Patients who would typically be recommended for hysterectomy
• • Planned delivery between 34w0d and 36w0d gestation.
• Exclusion Criteria:
• • Plan to delivery before neonatal viability (\<24 weeks gestation)
• • Hospitalized for antenatal hemorrhage
• • Have a low antenatal suspicion for PAS based on imaging
• • Are pregnant with multiples (twins, triplets)
• • Have a uterine fetal demise