Optimizing the Evaluation and Management of Patients With Suspected Choledocholithiasis

Launched by UNIVERSITY OF CALGARY · Nov 19, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the best ways to evaluate and manage patients who may have choledocholithiasis, which means stones in the common bile duct. This condition can lead to serious health problems if it's not treated properly. The trial is looking at different methods for diagnosing and deciding on treatment for patients who are suspected of having these stones, especially those who fall into an "intermediate risk" category. This group currently has limited options, often leading them to undergo a procedure called endoscopic retrograde cholangiopancreatography (ERCP), which is effective but comes with risks. Researchers are exploring whether looking at changes in liver enzymes could help improve the evaluation process for these patients.

To participate in this trial, individuals must be at least 18 years old and have suspected choledocholithiasis. They must also be able to give informed consent, meaning they understand what the trial involves. Those who have had previous treatments for choledocholithiasis or have certain other health conditions may not be eligible. Participants can expect to undergo additional tests that can help doctors better understand their condition and decide on the safest and most effective treatment. This research aims to improve the way doctors assess and treat patients with suspected bile duct stones, ultimately leading to better health outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with suspected choledocholithiasis, regardless of probability
• • age 18 years old or older
• • able to give informed consent to involvement (in the prospective validation phase).
• Exclusion Criteria:
• • Unable or unwilling to provide informed consent;
• • age \< 18 years;
• • suspected or proven cholangitis;
• • previous ERCP with sphincterotomy;
• • prior diagnosis or management of choledocholithiasis;
• • outpatient status;
• • out-of-province status (prohibiting full medical record access).