Application Registration Study of ILE in Patients With Acute Poisoning

Launched by PEKING UNION MEDICAL COLLEGE HOSPITAL · Dec 2, 2021

Keywords

ClinConnect Summary

This clinical trial is studying the use of intravenous fat emulsion (ILE) to treat patients who have been poisoned by certain fat-soluble substances, including specific pesticides. The goal is to see how effective ILE is in helping patients who haven't responded to traditional treatments, especially those experiencing serious symptoms like heart problems or shock. The researchers also want to understand how ILE works, develop better treatment procedures, and identify any side effects that may occur during the treatment.

To be eligible for this trial, participants must have a confirmed diagnosis of acute poisoning from fat-soluble drugs or pesticides and need ILE treatment due to ineffective conventional care. They should not have any major organ failures, serious mental health issues, or certain types of cancer. If someone decides to participate, they will receive ILE treatment and be monitored for its effects and any potential side effects. It's important to note that this trial is not yet recruiting participants, so there will be more information available in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Diagnosed as acute fat-soluble drug and organophosphorus (fat-soluble) pesticide poisoning;
• • 2. Conventional treatment is ineffective, especially for patients with circulatory failure, such as ventricular arrhythmia, shock, cardiac arrest, etc., who need intravenous fat emulsion treatment;
• • 3. Those who are not allergic to fat milk;
• • 4. Sign informed consent.
• Exclusion Criteria:
• • 1. Mergers with insufficiency of important organs;
• • 2. Patients with malignant tumors;
• • 3. Severe mental disorder affects the treatment;
• • 4. Those with incomplete clinical data.