Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry

Launched by KANSAS CITY HEART RHYTHM RESEARCH FOUNDATION · Dec 2, 2021

Keywords

ClinConnect Summary

The clinical trial titled "Myocarditis Causing Premature Ventricular Contractions: Insights From the MAVERIC Registry" is looking into the connection between a condition called myocarditis, which is inflammation of the heart muscle, and premature ventricular contractions (PVCs), which are extra heartbeats that can sometimes lead to heart rhythm problems. The study aims to understand how this inflammation may relate to PVCs, especially in patients who may or may not have reduced heart function.

To participate in this trial, you need to be over 18 years old and have experienced a significant number of PVCs, specifically 5,000 or more in a day. However, there are some health conditions that would exclude you from joining, such as a history of heart attacks or severe heart disease. If you qualify, you will undergo thorough testing to help determine if myocarditis is linked to your heart issues. It's important to note that this trial is not yet recruiting participants, so you would need to wait until it begins to find out more about getting involved.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients \> 18 years of age with mono-morphic or polymorphic PVC burden of ≥5000 in 24 hours.
• • Non-sustained VT was defined as ≥3 more consecutive beats lasting \<30 seconds
• Exclusion Criteria:
• • History of myocardial infarction,
• • Significant flow-limiting coronary artery disease (≥50% stenosis) on invasive coronary angiography or CT angiography,
• • History of revascularization,
• • Significant symptomatic atrial arrhythmias associated with LV dysfunction,
• • Severe valvular disease,
• • Cardiomyopathy attributed to toxins such as alcohol and illicit drugs,
• • History of cardiac arrest,
• • History of channelopathies or inherited arrhythmias.