The Home Blood Pressure (BP) Trial

Launched by UNIVERSITY OF WASHINGTON · Dec 2, 2021

Keywords

ClinConnect Summary

The Home Blood Pressure Trial is a research study aimed at understanding how managing blood pressure at home can help patients with end-stage renal disease who are on dialysis. The trial will involve 200 participants from the Seattle and San Francisco areas and will last for 10 months. It will compare two approaches to keeping blood pressure below 140 mmHg—one method focuses on patients checking their blood pressure at home, while the other involves measuring it before dialysis sessions. The goal is to see which approach helps reduce low blood pressure episodes during dialysis treatments.

To participate in this trial, individuals must be at least 18 years old, currently receiving in-center hemodialysis for at least three months, and have high blood pressure. They also need to be able to measure their blood pressure at home and at the dialysis clinic. Participants can expect regular check-ins to monitor their blood pressure and adjustments to their medications as needed. This study is particularly important as it seeks to improve the safety and comfort of dialysis patients by effectively managing their blood pressure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18 years or older
• • Undergoing in-center, thrice weekly hemodialysis for treatment of end stage renal disease (ESRD)
• • Greater than 3 months since initiation of dialysis
• • No anticipated change to peritoneal dialysis or kidney transplant within 10 months
• • Life expectancy greater than 10 months
• • Hypertension (defined as mean pre-dialysis SBP \> 140 mmHg over prior 2 weeks or taking BP medications)
• • Able to obtain/measure a brachial blood pressure at dialysis and at home (e.g., no left ventricular assist device, blood pressure not been taken routinely in lower extremity at dialysis unit)
• • No condition that the primary nephrologist or PIs feel precludes participation
• Exclusion Criteria:
• • Incarcerated or institutionalized (prohibits home blood pressure measurement)
• • Participating in another intervention study that may affect blood pressure
• • Pregnant or anticipated pregnancy or breastfeeding (as this will require increase to more than three times a week dialysis and/or preclude use of some classes of blood pressure medications)