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The Oxford Risk Factors And Non-Invasive Imaging Study

Launched by UNIVERSITY OF OXFORD · Dec 22, 2021

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

The Oxford Risk Factors And Non-Invasive Imaging Study (ORFAN) is a research project aimed at understanding the risk factors for heart and blood vessel diseases. The study will use CT scans and biological samples to find new indicators that help predict who might develop these conditions. Researchers hope that by gathering this information, they can improve how we identify and manage cardiovascular risks in different populations.

To participate in this study, you must be between 18 and 99 years old and be willing to give your consent to join. If you are currently facing active cancer or have previously taken part in other specific arms of the study, you may not be eligible. If you decide to participate, you can expect to undergo non-invasive imaging and provide some biological samples, which will help researchers gather vital information while ensuring your comfort and safety. This could contribute to better future treatments for cardiovascular diseases.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Inclusion Criteria for study Arms 1, 2 and 3:
  • Participant is willing and able to give informed consent for participation in the study.
  • Male or Female, aged 18 -99 years.
  • Inclusion Criteria for study Arm 4:
  • • Male or Female, aged 18 -99 years.
  • Exclusion Criteria:
  • Exclusion Criteria for Study Arms 1, 2 and 3:
  • Unable or unwilling to consent
  • Active cancer
  • Exclusion Criteria for Study Arm 4:
  • Participation in Study Arms 1, 2 or 3
  • Existing opt-out from use of data for research purposes

About University Of Oxford

The University of Oxford, a prestigious institution renowned for its excellence in research and education, serves as a leading clinical trial sponsor dedicated to advancing medical science and improving patient care. With a rich history of innovation and a multidisciplinary approach, the university leverages its extensive expertise in various fields, including medicine, public health, and biomedical research, to conduct rigorous clinical trials. Collaborating with healthcare professionals, industry partners, and regulatory bodies, the University of Oxford aims to translate groundbreaking research findings into effective therapies and interventions, contributing to the global effort of enhancing health outcomes.

Locations

Rochester, Minnesota, United States

Rochester, Minnesota, United States

Leeds, , United Kingdom

Shanghai, , China

Seoul, , Korea, Republic Of

Birmingham, , United Kingdom

Leuven, , Belgium

Liverpool, , United Kingdom

Tianjin, , China

Glasgow, , United Kingdom

Ulm, , Germany

Glasgow, , United Kingdom

London, , United Kingdom

London, , United Kingdom

Cambridge, , United Kingdom

Sittard, , Netherlands

Oxford, , United Kingdom

Abu Dhabi, , United Arab Emirates

ōita, , Japan

Milton Keynes, , United Kingdom

Bath, , United Kingdom

Adelaide, , Australia

Amsterdam, , Netherlands

Sydney, , Australia

Bethesda, Maryland, United States

Cleveland, Ohio, United States

Aix En Provence, , France

Erlangen, , Germany

Athens, , Greece

Budapest, , Hungary

Milan, , Italy

Târgu Mureş, , Romania

Birmingham, , United Kingdom

Edinburgh, , United Kingdom

Leicester, , United Kingdom

London, , United Kingdom

Manchester, , United Kingdom

Wolverhampton, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Antoniades

Principal Investigator

University of Oxford

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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