Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Launched by LESLIE SON · Dec 15, 2021

Keywords

ClinConnect Summary

This clinical trial is studying how well two different pain relief methods work after surgery for inguinal (groin) or ventral (abdominal wall) hernias. Specifically, it compares a newer medication called Exparel to a traditional anesthetic called Marcaine when used in a specific type of pain management technique called a TAP block. The goal is to find out which method provides better pain control after surgery.

To be eligible for this trial, participants need to be at least 18 years old and have a hernia that requires surgery. However, people with certain conditions, like severe chronic pain or specific hernia sizes, may not qualify. If someone joins the trial, they can expect to receive either the Exparel or the Marcaine TAP block before their surgery to help manage pain afterward. The trial is currently recruiting participants, so it's a good opportunity for those who meet the criteria to contribute to important research on pain management in hernia repairs.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age or older
• • Have a ventral or inguinal hernia requiring surgical repair
• Exclusion Criteria:
• • Less than 18 years of age
• • Chronic pain patients
• • Having a defect \>10 cm in transverse dimension
• • Having a defect \<4 cm
• • Has an allergy to bupivacaine
• • Has recurrent hernias as per medical history
• • A TAP block performed at any time aside from just prior to the start of the procedure
• • If bupivacaine is mixed with other anesthetics
• • Under the instance of an emergency surgery (trauma)
• • Concomitant surgery
• • History of EtOH abuse
• • History of liver/kidney dysfunction
• • If the procedure must be converted to open
• • Inidividual's weight \< 50kg
• • Individual's BMI \> 45