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Search / Trial NCT05179083

Exercise for Brain Regeneration in Epilepsy

Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Dec 20, 2021

Trial Information

Current as of November 13, 2025

Recruiting

Keywords

Exercise Neurogenesis Mesial Temporal Lobe Epilepsy Regeneration Cognition Electrophysiology

ClinConnect Summary

This clinical trial, titled "Exercise for Brain Regeneration in Epilepsy," is looking at how exercise can help improve brain health in people with temporal lobe epilepsy. The researchers believe that regular aerobic exercise may help the brain grow new nerve cells, which could lead to better memory and cognitive function. This is especially important as many people with neurological disorders face challenges like memory loss and cognitive decline.

To join the study, participants must be at least 18 years old and have a type of epilepsy that doesn't respond to standard treatments. They should also be considered for a specific type of brain surgery. However, those over 65, pregnant women, and individuals with certain medical conditions that prevent them from exercising cannot participate. If you join the study, you can expect to follow an exercise program designed to see how it affects your brain health. The trial is currently recruiting participants, so it’s a great opportunity for those who meet the criteria and want to contribute to important research.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age of 18 years or older
  • Medically resistant mesial temporal lobe epilepsy
  • Candidacy for standard or selective temporal lobectomy
  • Exclusion Criteria:
  • Age of older than 65 years
  • Pregnancy
  • Physical disabilities or medical conditions preventing from participation in exercise program
  • Inability to receive exercise equipment at home
  • Cognitive/developmental disabilities restricting the participation in exercise program

About University Of Southern California

The University of Southern California (USC) is a prestigious research institution located in Los Angeles, California, known for its commitment to advancing knowledge and innovation in various fields, including medicine and health sciences. As a clinical trial sponsor, USC leverages its extensive resources, interdisciplinary expertise, and state-of-the-art facilities to conduct cutting-edge research aimed at improving patient outcomes and public health. The university fosters collaboration among its diverse faculty and students, ensuring a dynamic environment for the development and implementation of clinical studies that adhere to the highest ethical and scientific standards. Through its clinical trials, USC aims to contribute to the advancement of medical science and the translation of research findings into practical applications that benefit communities locally and globally.

Locations

Los Angeles, California, United States

Patients applied

0 patients applied

Trial Officials

Jonathan J Russin, MD

Principal Investigator

University of Southern California

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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