Comparing Two Ways to Manage Head and Neck Lymphedema
Launched by ABRAMSON CANCER CENTER AT PENN MEDICINE · Jan 5, 2022
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different ways to help manage lymphedema, which is swelling caused by a buildup of lymph fluid, in patients who have survived head and neck cancer. The study will compare receiving treatment at a clinic, known as clinic-based complete decongestive therapy (CDT), with a combination of home and clinic treatment, called hybrid CDT. The goal is to see which method helps reduce swelling, relieve symptoms, improve daily activities, and decrease the need for additional healthcare visits.
To participate in this trial, individuals must be over 18 years old and have completed their head and neck cancer treatment within the last 24 months. They should also have a diagnosis of head and neck lymphedema and be able to perform some self-care techniques at home. Participants will need access to an electronic device and the internet for the home-based portion of the study. If you have any recent infections in the head or neck, severe swelling, or specific health conditions, you may not be eligible. This trial is currently recruiting participants of all genders, and it offers an opportunity to explore effective ways to manage lymphedema after cancer treatment.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • \>18 years of age
- • \<=24 months post-HNC treatment
- • Diagnosis of head and neck lymphedema and referral by their oncology providers
- • Able to perform self-manual lymphatic drainage
- • Having an electronic device (a computer, tablet, iPad, laptop, or smartphone) and internet access at home
- Exclusion Criteria:
- • Active infection in soft tissues in the head and neck region
- • History of moderate or severe carotid artery occlusion
- • Significantly severe lymphedema (e.g., severe periorbital swelling)
- • Conditions impacting the safe delivery of lymphedema therapy
About Abramson Cancer Center At Penn Medicine
The Abramson Cancer Center at Penn Medicine is a leading academic institution dedicated to advancing cancer research, treatment, and prevention. As part of the University of Pennsylvania, the center integrates cutting-edge scientific discovery with comprehensive clinical care, offering patients access to innovative therapies and clinical trials. Renowned for its multidisciplinary approach, the Abramson Cancer Center collaborates with experts across various specialties to deliver personalized treatment plans while fostering a supportive environment for patients and their families. Committed to improving outcomes and quality of life for cancer patients, the center is at the forefront of groundbreaking research initiatives and educational programs aimed at transforming cancer care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Philadelphia, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Philadelphia, Pennsylvania, United States
Cherry Hill, New Jersey, United States
Philadelphia, Pennsylvania, United States
Willow Grove, Pennsylvania, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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