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Search / Trial NCT05182229

Comparing Two Ways to Manage Head and Neck Lymphedema

Launched by ABRAMSON CANCER CENTER AT PENN MEDICINE · Jan 5, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at two different ways to help manage lymphedema, which is swelling caused by a buildup of lymph fluid, in patients who have survived head and neck cancer. The study will compare receiving treatment at a clinic, known as clinic-based complete decongestive therapy (CDT), with a combination of home and clinic treatment, called hybrid CDT. The goal is to see which method helps reduce swelling, relieve symptoms, improve daily activities, and decrease the need for additional healthcare visits.

To participate in this trial, individuals must be over 18 years old and have completed their head and neck cancer treatment within the last 24 months. They should also have a diagnosis of head and neck lymphedema and be able to perform some self-care techniques at home. Participants will need access to an electronic device and the internet for the home-based portion of the study. If you have any recent infections in the head or neck, severe swelling, or specific health conditions, you may not be eligible. This trial is currently recruiting participants of all genders, and it offers an opportunity to explore effective ways to manage lymphedema after cancer treatment.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • \>18 years of age
  • \<=24 months post-HNC treatment
  • Diagnosis of head and neck lymphedema and referral by their oncology providers
  • Able to perform self-manual lymphatic drainage
  • Having an electronic device (a computer, tablet, iPad, laptop, or smartphone) and internet access at home
  • Exclusion Criteria:
  • Active infection in soft tissues in the head and neck region
  • History of moderate or severe carotid artery occlusion
  • Significantly severe lymphedema (e.g., severe periorbital swelling)
  • Conditions impacting the safe delivery of lymphedema therapy

About Abramson Cancer Center At Penn Medicine

The Abramson Cancer Center at Penn Medicine is a leading academic institution dedicated to advancing cancer research, treatment, and prevention. As part of the University of Pennsylvania, the center integrates cutting-edge scientific discovery with comprehensive clinical care, offering patients access to innovative therapies and clinical trials. Renowned for its multidisciplinary approach, the Abramson Cancer Center collaborates with experts across various specialties to deliver personalized treatment plans while fostering a supportive environment for patients and their families. Committed to improving outcomes and quality of life for cancer patients, the center is at the forefront of groundbreaking research initiatives and educational programs aimed at transforming cancer care.

Locations

Philadelphia, Pennsylvania, United States

Philadelphia, Pennsylvania, United States

Philadelphia, Pennsylvania, United States

Philadelphia, Pennsylvania, United States

Cherry Hill, New Jersey, United States

Philadelphia, Pennsylvania, United States

Willow Grove, Pennsylvania, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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