Inflammation and Clotting Abnormalities in Aneurysmal Coronary Artery Disease

Launched by JOHN PAUL II HOSPITAL, KRAKOW · Jan 6, 2022

Keywords

ClinConnect Summary

The CARE-ANEURYSM trial is studying how inflammation and blood clotting problems are related to certain heart conditions, specifically aneurysms in the coronary arteries and abdominal aortic aneurysms. Researchers want to understand these issues better by comparing patients with coronary artery aneurysms to those with abdominal aortic aneurysms or other types of coronary artery disease. This information could help improve treatments and outcomes for patients with these conditions.

To be eligible for this study, participants should be between 18 and 85 years old and have a confirmed diagnosis of either a coronary artery aneurysm, an abdominal aortic aneurysm, or coronary artery disease. Participants will undergo various evaluations, but they need to be in good health overall and not currently taking certain medications that could affect the study. If you or someone you know meets these criteria, joining the trial could contribute to important research that helps others with similar health issues in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18-85 years old
• • Angiographically confirmed coronary artery ectasia or aneurysm (Arm I)
• • Abdominal aortic aneurysm (Arm II)
• • Angiographically confirmed coronary artery disease (Arm III)
• Exclusion Criteria:
• • Less than 12 months from ACS
• • Actual oral anticoagulant therapy
• • Actual antiplatelet therapy other than aspirin
• • Heart failure NYHA IV
• • Untreated hyperthyroidism or hypothyroidism
• • Severe comorbidities
• • Lack of consent