SPECT/CT Bone Scan Quantification Surgery

Launched by CENTRAL HOSPITAL, NANCY, FRANCE · Dec 21, 2021

Keywords

ClinConnect Summary

This clinical trial is investigating how a specialized imaging technique called SPECT/CT bone scan can help identify patients who are likely to benefit from a specific back surgery called lumbar arthrodesis. This surgery is often recommended for individuals with persistent back pain, typically due to conditions like degenerative disc disease or spondylolisthesis, where the spine becomes unstable. The researchers hope that by measuring certain values from the bone scan before surgery, they can better predict which patients will have a good response to the operation.

To participate in this trial, individuals must be at least 18 years old and have experienced back pain for at least three months. They should not have a history of certain spine-related issues or other medical conditions that could complicate the trial. Participants will receive detailed information about the study and must give their consent to join. If eligible, they can expect to undergo a SPECT/CT bone scan and then, if they choose to proceed, the surgery performed by experienced neurosurgeons. This research aims to improve outcomes for patients undergoing back surgery by better understanding who will benefit the most.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Persons with back pain for at least 3 months (presumed to be due to degenerative disc disease or spondylolisthesis).
• * Persons who have received full information about the organisation of the research and have signed the informed consent and :
• • Age ≥ 18 years, having read and understood the information document.
• • Affiliated to a social security scheme.
• • Lumbar arthrodesis involving a maximum of 2 floors.
• • Standardized lumbar arthrodesis surgery performed by one of the three senior neurosurgeons of the neurosurgery department of the Nancy CHRU, using similar surgical techniques.
• Exclusion Criteria:
• • Low back pain of neuropathic origin. The Neuropathic Pain Scale 4 questionnaire is used to diagnose neuropathic pain (score is ≥ 4/10)
• • History of lumbar spine surgery
• • Presence of other pathologies responsible for lumbar pain (multistage discopathies, ankylosing spondylitis, spondylodiscitis, rheumatoid arthritis, vertebral compression, vertebral metastasis, narrow lumbar canal, scoliosis, spondylolisthesis by isthmic lysis)
• • Pregnant women or women of childbearing age without suitable contraception or nursing mothers.
• • Unstable medical condition and/or inability to remain immobile in supine position during recordings.
• • Known allergy to any component of the radiopharmaceutical (TECHNESCAN HDP).
• • Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code.
• • Persons deprived of their liberty by a judicial or administrative decision, persons under psychiatric care by virtue of Articles L. 3212-1 and L. 3213-1.
• • Persons of full age who are unable to express their opposition.