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Search / Trial NCT05184790

LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New Technology

Launched by UNIVERSITY OF SYDNEY · Jan 6, 2022

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Radiation Therapy Markerless Tracking

ClinConnect Summary

The LEARN trial is studying a new technology that uses a special method to track the movement of tumors and nearby organs during radiation therapy without needing any markers attached to the body. This real-time tracking can help doctors deliver more accurate treatment for various types of cancer, including breast, prostate, brain, kidney, liver, pancreas, and spinal cancers, as well as for patients with heart rhythm problems. The goal is to collect and analyze patient data to improve this tracking method over time.

To be eligible for this study, participants should be adults (18 years or older) who are scheduled to receive radiation therapy for one of the cancers mentioned above at a participating center. They will also need to undergo certain imaging tests as part of their treatment. If you decide to join the trial, you can expect to continue with your regular treatment while the new tracking method is tested alongside it, and your involvement will help improve future cancer care.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Will receive radiation therapy for brain, breast, head and neck, kidney, liver, pancreas, prostate, spine cancer treatment or cardiac arrhythmia treatment at a participating centre.
  • Will receive CT planning, and a cone beam CT scan for at least one fraction of radiation therapy.
  • Will receive intrafraction x-ray imaging for the liver, pancreas, prostate, spine cancer treatment or cardiac arrhythmia treatment. As intrafraction imaging is not common standard of care for brain, breast, head and neck and kidney cancer treatments there is no requirement to have intrafraction x-ray imaging data for these anatomical sites.
  • Provides written informed consent.
  • Exclusion Criteria:
  • Less than 18 years of age

About University Of Sydney

The University of Sydney is a leading research institution in Australia, renowned for its commitment to advancing medical science and improving healthcare outcomes through innovative clinical trials. With a robust infrastructure and a multidisciplinary team of experts, the university fosters a collaborative environment that integrates cutting-edge research with clinical practice. The institution emphasizes ethical standards, patient safety, and scientific rigor in its trials, aiming to translate findings into real-world applications that benefit diverse populations. Through its dedication to excellence and impact, the University of Sydney continues to contribute significantly to the fields of medicine and public health.

Locations

Melbourne, , Australia

Woolloongabba, Queensland, Australia

Saint Leonards, New South Wales, Australia

Melbourne, Victoria, Australia

Patients applied

0 patients applied

Trial Officials

Paul Keall

Study Chair

Professor

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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