A Single-center Study on the Effect of Systemic/Selective Lymph Node Dissection on the Prognosis of Ground Glass Nodules Smaller Than 3cm and With Components With Consolidation/Tumor Ratio Between 0.5-1

Launched by SHANGHAI ZHONGSHAN HOSPITAL · Dec 28, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at how certain types of surgery, called systemic or selective lymph node dissection, may affect the outcomes for patients with specific lung nodules known as ground glass nodules (GGNs). These nodules are small and can be seen on a special type of lung scan. The trial will focus on nodules that are smaller than 3 centimeters and have a certain amount of solid tissue within them. The goal is to understand if the surgery can help improve recovery and prognosis for these patients.

To qualify for this study, participants need to be between 25 and 75 years old and must have been diagnosed with a GGN using a detailed lung scan within the month before surgery. They should also be able to tolerate a specific type of lung surgery called lobectomy, where only part of the lung is removed. However, people who have had previous lung surgery, have other serious health conditions, or have certain types of tumors won’t be able to participate. This trial is not yet recruiting, but it aims to provide valuable information for patients with these specific lung nodules and may help guide future treatment options.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Patients enrolled in the study must meet all of the following conditions:
• • 1.Aged between 25 and 75 years;
• • 2. GGO is diagnosed by thin-section lung CT (thickness \<1.5mm) within one month before surgery;
• • 3. The maximum diameter of the GGO is smaller than 3cm;
• • 4. The solid component in GGO between 50%-100%;
• • 5. Preoperative examination showed that the patient could tolerate lobectomy;
• • 6. The patient is able to understand and comply with the study and has provided written informed consent.
• Exclusion Criteria:
• Patients meeting any of the following criteria are not eligible for this trial:
• • 1. Patients with a history of lung surgery;
• • 2. Postoperative pathology showed non-primary lung cancer;
• • 3. The scope of surgical resection is larger than one lung lobe;
• • 4. Patients with a history of other tumors;
• • 5. Patients with severe complications (coronary heart disease, valvular heart disease, end-stage renal disease, severe liver cirrhosis);
• • 6. Unable to cooperate with the researchers because of dementia or cognitive decline
• • 7. Other situations that are not in conformity with the standards and requirements of this trial.