Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness

Launched by JOHANNES GUTENBERG UNIVERSITY MAINZ · Jan 6, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new method to help doctors predict how well a patient’s body will respond to fluids during major abdominal surgery. Specifically, it looks at a measurement called carotid doppler peak velocity, which is a way to assess blood flow in the neck. By observing how this measurement changes with breathing, researchers hope to determine if a patient will benefit from receiving extra fluids during surgery.

To be eligible for this study, participants need to be between 18 and 80 years old and scheduled for major abdominal surgery. Those who are pregnant, have certain heart or lung conditions, or are significantly overweight may not be able to participate. If someone joins the study, they can expect to undergo non-invasive tests to measure blood flow before and during their surgery, helping to make more informed decisions about their care. This trial is currently recruiting participants, and it aims to enhance the safety and effectiveness of fluid management in surgical patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18-80 years
• • written informed consent
• • scheduled major abdominal surgery
• Exclusion Criteria:
• • Age \<18 or \>80 years
• • pregnancy
• • SIRS or sepsis
• • any kind of cardiac arrhythmia
• • known valve disease
• • known heart failure
• • any kind of known carotid stenosis
• • carotid doppler peak velocity \>182 cm/s before baseline measurement (expected stenosis)
• • missing indication for invasive arterial blood pressure monitoring (IBP) not related to the study
• • peripheral artery disease (PAD)
• • BMI \> 35 kg/m2
• • intraabdominal hypertension
• • ASA-PSC of 4
• • severe lung disease (e.g. COPD grade 3, fibrosis)
• • esophageal disease of any kind
• • participation in another clinical study