Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Jan 11, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how a special treatment program delivered through phone or online can help patients with chronic liver disease who are also struggling with unhealthy alcohol use. Participants in the trial will be divided into two groups: one group will receive a stepped alcohol treatment that includes motivational support and a referral to addiction specialists if needed, while the other group will receive standard care. The study aims to see how effective this approach is over 6 and 12 months.

To be eligible for the trial, participants must be at least 18 years old, have chronic liver disease, and show unhealthy patterns of alcohol use, which means drinking more than moderate amounts in the past month. They should also be able to access a phone or a device like a computer or smartphone for the sessions. Participants will be monitored for their progress, and those who qualify will be informed about what to expect during the study. This research could provide valuable insights into improving care for people with liver disease and alcohol-related issues.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • 1. Men and women age ≥ 18 years.
• • 2. Diagnosis of chronic liver disease (CLD).
• • 3. Unhealthy alcohol use, defined as more than moderate amount of alcohol use within the prior 30 days by National Institute on Alcohol Abuse and Alcoholism (NIAAA) criteria defined as on average more than 1 drink/day (7 drinks per week) for women and more than 2 drinks per day (14 drinks per week) for men, or on average at least one heavy drinking day (4+ drinks in a day for women and 5+ for men) per week in the prior 30 days. A standard drink is \~14 g of alcohol.
• • 4. Ability to access a telephone or a digital device (i.e., computer, tablet or smart phone).
• Exclusion criteria:
• • 1. Severe medical or psychiatric conditions or evidence of acute alcohol intoxication preventing participation in the study
• • 2. Are currently enrolled in formal treatment for unhealthy alcohol use, excluding self or mutual-help groups (e.g., Alcoholics Anonymous).
• • 3. Women who are pregnant or breastfeeding or unwilling to use birth control.
• • 4. Language preference other than English, Spanish or Chinese.
• • 5. Unwilling or unable to provide informed consent.