AutoInflammatory Disease Alliance Registry (AIDA)

Launched by UNIVERSITY OF SIENA · Jan 6, 2022

Keywords

ClinConnect Summary

The AutoInflammatory Disease Alliance Registry (AIDA) is a clinical trial designed to gather important information about various rare autoinflammatory diseases, which are conditions that cause repeated episodes of inflammation without an infection. These diseases include hereditary periodic syndromes like Behçet's disease, Still's disease, and PFAPA syndrome, among others. The goal of this trial is to create a global registry that collects details about patients' demographics, genetics, symptoms, and treatments to improve our understanding and management of these conditions.

To participate in this study, individuals must have a confirmed diagnosis of a specific autoinflammatory disease, such as familial Mediterranean fever, Behçet's disease, or non-infectious uveitis, among others. The trial is open to people of all ages and genders, as long as they can provide consent. Participants can expect to contribute to a valuable resource that could help researchers find better treatments for these rare diseases. It’s important to note that participants need to provide informed consent to join the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • to be diagnosed with a monogenic AID according to the clinical phenotype and the detection of a confirmative genotype;
• • to be diagnosed with clinical familial Mediterranean fever or Behçet's disease or Still disease or PFAPA syndrome or Schnitzler's disease or CRMO according to the corresponding clinical diagnostic and/or classification criteria;
• • to be diagnosed with undifferentiated systemic AID;
• • to be diagnosed with non-infectious uveitis according to the standardization for uveitis nomenclature (SUN) criteria;
• • to be diagnosed with anterior or posterior non-infectious scleritis;
• • to be diagnosed with spondyloarthritis according to ASAS and/or New York criteria;
• • to be diagnosed with Castleman disease;
• Exclusion Criteria:
• • - informed consent/assent not provided by the patient and/or his/her legal representative.