Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers

Launched by M.D. ANDERSON CANCER CENTER · Jan 11, 2022

Keywords

ClinConnect Summary

This clinical trial is studying two surgical methods for treating certain types of stomach cancer: minimally invasive proximal gastrectomy (MIPG) and minimally invasive total gastrectomy (MITG). The goal is to compare how these two procedures affect patients' symptoms after surgery. Researchers want to find out which method might lead to better outcomes for patients diagnosed with non-metastatic gastric cancer or gastroesophageal junction (GEJ) adenocarcinoma who are planning to have surgery to try to cure their cancer.

To participate in the trial, patients need to be at least 18 years old and able to read and speak English, Spanish, Korean, or Japanese, depending on where they are enrolled. They must have a confirmed diagnosis of stomach cancer and be scheduled for one of the surgical procedures. Participants can expect to be monitored closely during and after their surgery to assess their symptoms and recovery. It’s important to note that some patients, such as those with certain health issues or who are pregnant, may not be eligible to join the study.

Gender

ALL

Eligibility criteria

• Inclusion:
• • 1. Able to speak and read English, Spanish, Japanese or Korean
• • 2. Participants with a biopsy-confirmed diagnosis of non-metastatic gastric or GEJ adenocarcinoma, who are scheduled to undergo MIPG or MITG for curative-intention
• • 3. Age ≥ 18
• Exclusion:
• • 1. Participants with known malabsorption syndromes or a lack of physical integrity of the upper gastrointestinal tract
• • 2. Participants with known narcotic dependence, with average daily dose \> 5 mg oral morphine equivalent
• • 3. Participants deemed unable to comply with study and/or follow-up procedures, at investigators' discretion
• • 4. Participants who are pregnant (since are excluded from receiving standard-of-care MIPG or MITG)