Is Myocardial Stunning Induced by Continuous Renal Replacement Therapy a Reality in Critically Ill Patients?

Launched by HOSPICES CIVILS DE LYON · Jan 25, 2022

Keywords

ClinConnect Summary

This clinical trial is looking into a condition called myocardial stunning, which can occur in critically ill patients undergoing a specific type of kidney treatment known as Continuous Renal Replacement Therapy (CRRT). Essentially, the researchers want to find out if CRRT can cause temporary heart issues, regardless of changes in blood flow to the heart. They believe that this might happen more often than previously thought and could be related to poor blood flow in other parts of the body.

To participate in this study, individuals need to be over 18 years old and diagnosed with a severe type of kidney injury (grade 3 acute kidney injury). They must also require kidney treatment as decided by their doctor, but not in an emergency situation. Participants will undergo assessments to see if they experience any effects on their heart while receiving this kidney treatment. This study is currently recruiting participants and aims to provide more information that could help improve care for patients with kidney issues in critical conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \> 18 years old
• • Acute Kidney Injury grade 3 (KDIGO)
• • Indication for renal replacement therapy for the clinician in charge
• Exclusion Criteria:
• • Emergency indication to renal replacement therapy (pH\<7.15, Kaliemia \> 6mmol/L, refractory pulmonary oedema)
• • Poor echogenicity with speckle tracking analysis failure
• • Chronic hemodialysis
• • Extra corporeal membrane oxygenation, left ventricular assist device.