POEM + F for Achalasia - a Pilot Study

Launched by CHINESE UNIVERSITY OF HONG KONG · Jan 15, 2022

Keywords

ClinConnect Summary

The POEM + F for Achalasia study is a clinical trial that aims to explore a new treatment approach for patients with achalasia, a condition that affects the ability to swallow due to problems with the esophagus. This trial will look at a procedure called per-oral endoscopic myotomy (or POEM) combined with another technique called endoscopic fundoplication. This combination may help reduce a common issue after the POEM procedure, which is reflux (when stomach acid comes back up into the esophagus). In this pilot study, researchers will recruit 10 patients to see how well this new approach works using a special device called the X-tack anchoring device.

To be eligible for this trial, patients must be at least 18 years old and have been diagnosed with achalasia. They should not have had any previous treatments for achalasia or certain types of abdominal surgery. If you participate, you can expect to undergo the POEM procedure along with the fundoplication, and the team will closely monitor your progress. This study is currently recruiting participants, and it's an opportunity to contribute to understanding and improving treatments for achalasia.

Gender

ALL

Eligibility criteria

• • Inclusion criteria
• • 1. Patients with achalasia diagnosed with high resolution manometry, scheduled for elective per-oral endoscopic myotomy
• • 2. Age \>18
• • Exclusion criteria
• • 1. Prior treatment for achalasia, including surgical myotomy, dilatation or POEM.
• • 2. Prior upper abdominal surgery
• • 3. Other cases deemed by the examining physician as unsuitable for safe treatment
• • 4. Patients who refused to participate