Reconstruction in Extended MArgin Cancer Surgery

Launched by UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST · Jan 20, 2022

Keywords

ClinConnect Summary

The clinical trial titled "Reconstruction in Extended Margin Cancer Surgery" is looking at how different methods of surgery and reconstruction can affect patients with advanced pelvic cancers. These cancers are tough to treat and often require removing several organs and tissues, which can lead to complications and impact a patient’s recovery and quality of life. The study aims to gather information on how often these complications occur, the overall health and well-being of patients after surgery, and the costs associated with different reconstruction techniques. By doing this, researchers hope to help doctors and patients make better choices about treatment options.

To participate in this trial, individuals must be 18 years or older and have undergone specific types of surgeries called pelvic exenteration or abdominoperineal excision at the participating hospitals. Participants will be asked to share their experiences, complete health questionnaires, and may take part in interviews to provide deeper insights into their recovery and quality of life. This study is important as it aims to improve the care and outcomes for patients dealing with complex pelvic cancers.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male and female patients aged 18 or older
• • Patients that have undergone pelvic exenteration or abdominoperineal excision at participating sites, at any time, that have complete data (work package 1 - Colorectal Surgery Database)
• • Patients undergoing pelvic exenteration or abdominoperineal excision at participating sites (work package 2 - prospective study)
• • Patients that have already had pelvic exenteration or abdominoperineal resection that can speak English (work package 3 - mixed-methods study)
• Exclusion Criteria:
• • Patients eligible for, but that are unfit, decline or are not offered abdominoperineal excision or pelvic exenteration surgery
• • Patients that undergo surgery by an intersphincteric abdominoperineal resection approach
• • Patients that are unable to complete the questionnaire over the telephone or online with a researcher
• • Patients unable or unwilling to provide informed consent
• • Patients that are prisoners in the custody of HM Prison Service or who are offenders supervised by the probation service