Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)

Launched by COLUMBIA UNIVERSITY · Jan 21, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring a new imaging technique called Harmonic Motion Imaging (HMI) to help guide and monitor a type of treatment called Focused Ultrasound Surgery (FUS) for women with breast tumors. The study aims to see if HMI can provide useful information about how the treatment is working for patients with benign tumors, like fibroadenomas, or early-stage breast cancer that has not spread to other parts of the body.

To participate in the trial, women must be at least 18 years old and have either a fibroadenoma or stage I breast cancer. They should be planning to have surgery to remove their tumor, which should be located deeper than 1 cm below the skin and between 2-5 cm in size. However, pregnant women, those with breast implants, or anyone who has had previous treatment on the targeted breast area cannot join. Participants will undergo imaging and treatment, and the study will help researchers understand how effective this new method is in monitoring tumor treatment.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women age ≥18
• • Patients with fibroadenoma (benign tumor) or early-stage, non-metastatic breast cancer (stage I without the involvement of axillary lymph nodes)
• • Scheduled to receive surgical resection of the tumor by the clinical care team (ideal target lesion upper boundary should be deeper than 1 cm below the skin, and the ideal size of the lesion should be 2-5 cm in diameter)
• Exclusion Criteria:
• • Pregnant or lactating women
• • Patients with breast implants
• • Patients with a history of laser or radiation therapy to the targeted breast
• • Patients who have received or are scheduled to receive thermal ablation or treatment of the tumor (other than surgery) as part of clinical care