Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'

Launched by ACADEMISCH MEDISCH CENTRUM - UNIVERSITEIT VAN AMSTERDAM (AMC-UVA) · Feb 1, 2022

Keywords

ClinConnect Summary

Study procedures On the first day of admission, all the patients scheduled for cardiac surgery with an on-pump procedure will be asked for a consent for anonymous using of their information. Patients giving permission will be screened for participation in this study, and those fulfil the inclusion/exclusion criteria will be included for further research.

Blood ketone will be measured with StatStrip Glucose/Ketone Meters (Nova biomedical, United Kingdom) using sample leftover from blood gas analysis. No extra blood draw is needed. The levels of ketones will be measured at four time points:
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Gender

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Eligibility criteria

• In order to be eligible to participate in this study, a subject must meet all of the following criteria:
• • Inclusion Criteria
• • Aged eighteen years or older
• • Scheduled for open heart surgery
• • Exclusion criteria
• • Diagnosed with type 1 diabetes mellitus or latent auto-immune diabetes in adults
• • Recently used sodium glucose transport co-enzyme 2 (SGLT-2i's) within 2 weeks before surgery)
• • History of recurrent ketoacidosis (two times or more within three months)
• • Emergency surgery
• • (Suspected) pregnancy