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Search / Trial NCT05229185

Error-enhancement for Arm Rehabilitation Post Stroke

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Feb 7, 2022

Trial Information

Current as of August 27, 2025

Completed

Keywords

Upper Limb Neurorehabilitation Error Enhancement Robotic Treatment

ClinConnect Summary

The overall aim of this study is to gain knowledge into the potential of error-enhancement robot training in patients with upper limb impairments in the chronic phase after stroke. Error-enhancement is characterized as unexpected external perturbation forces acting upon the upper limb during a reaching movement, causing the upper limb to deflect from the reaching pathway, and this results in errors. If one allows for repetitive reaching performance with the same systematic perturbation forces, then a decrease in errors and improvement in movement performance is expected. The robot used for ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures
  • 2. First stroke, confirmed by neurologist based on clinical and/or imaging findings
  • 3. Ischemic/hemorrhagic stroke, at least more than six months ago
  • 4. Stroke affecting the dominant/non-dominant upper limb (unilateral weakness)
  • 5. Less than 85 years old
  • 6. Having a motor impairment yet no severe spasticity in the upper limb: be able to open and close the hand 5 times and be able to flex and extend the elbow 2 times but score less than 66 (maximum) on the Fugl-Meyer Assessment.
  • Exclusion Criteria:
  • 1. Having sensory aphasia (evaluated by item 9 of the National Institutes of Health Stroke Scale)
  • 2. Having apraxia (evaluated by the apraxia screen of TULIA)
  • 3. Having neglect (evaluated by the Star Cancellation Test)
  • 4. Cognitive deficit with a score under 24 out of 30 on the Mini-mental State Examination
  • 5. Shoulder pain (yes/no)
  • 6. Providing no informed consent

About Universitaire Ziekenhuizen Ku Leuven

Universitaire Ziekenhuizen KU Leuven is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. Affiliated with KU Leuven, one of Europe’s premier universities, the institution integrates cutting-edge scientific inquiry with high-quality patient care. It plays a pivotal role in the development and implementation of clinical trials, fostering collaboration between researchers, healthcare professionals, and industry partners to translate scientific discoveries into effective treatments. The hospital's multidisciplinary approach ensures comprehensive patient safety and ethical standards, positioning it as a trusted sponsor in the realm of clinical research.

Locations

Leuven, , Belgium

Patients applied

0 patients applied

Trial Officials

Geert Verheyden

Principal Investigator

KU Leuven

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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