Conservative Treatment of PAS With or Without IIL
Launched by TANTA UNIVERSITY · Feb 9, 2022
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at a condition called placenta accreta, which occurs when the placenta attaches too deeply into the uterine wall. The researchers want to find out if a procedure called internal iliac ligation (IIL), which involves tying off certain blood vessels, provides added benefits when treating this condition compared to traditional methods. The trial is currently recruiting participants, specifically women under the age of 35, who have been diagnosed with placenta accreta before delivery and plan to have a cesarean section before 37 weeks of pregnancy. Participants should also have had no more than three previous cesarean sections and want to keep their ability to have children in the future.
If you join this study, you will be monitored closely to see how the treatment works for you. It’s important to note that this trial is not for everyone—for instance, women with certain blood disorders, those taking blood-thinning medications, or those who have completed their families cannot participate. The goal is to better understand the best ways to manage placenta accreta while helping women preserve their fertility.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Age under 35 years old.
- • 2. Prenatally diagnosed placenta accreta .
- • 3. Planned caesarean section ≤ 37 wks .
- • 4. ≤ previous 3 ceserian sections .
- • 5. Placenta accretta spectrum grade 1 , 2 ,3 .
- • 6. Patients who want to preserve their fertility.
- • 7. Patients who refuse hysterectomy .
- Exclusion Criteria:
- • 1. Cases with high risk of intraoperative blood loss as hemorrhagic disorders and thrombocytopenia .
- • 2. Cases on anticoagulant therapy.
- • 3. Patients who completed her family.
- • 4. Hemodynamicaly unstable patients.
- • 5. Finally cases who refused to get enrolled in the study.
About Tanta University
Tanta University is a prestigious academic institution located in Egypt, dedicated to advancing medical research and education. As a clinical trial sponsor, Tanta University leverages its extensive resources and expertise to conduct innovative research initiatives aimed at improving health outcomes. The university collaborates with a network of healthcare professionals, researchers, and institutions to facilitate rigorous clinical trials across various medical disciplines. Committed to ethical standards and scientific integrity, Tanta University strives to contribute to the global body of knowledge while fostering the next generation of medical professionals.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tanta, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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