Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Launched by MASSACHUSETTS GENERAL HOSPITAL · Feb 2, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at different types of palliative care for patients with a serious blood cancer called acute myeloid leukemia (AML). Palliative care focuses on improving the quality of life for patients by helping manage symptoms, mood, and overall well-being, especially during challenging times like treatment or at the end of life. The study is comparing standard palliative care provided by specialists to a more general type of palliative care to see which one works better for patients.

To be eligible for this trial, participants must be at least 18 years old and hospitalized with high-risk AML, which includes those newly diagnosed at age 60 or older, those with previous blood disorders, or those whose disease has returned after treatment. Patients should also be undergoing intensive treatment, such as chemotherapy. The study is open to patients of any gender, and it also involves caregivers who are close to the patient and can offer support. If you join this study, you can expect regular assessments to see how the different types of care impact your comfort and quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient Inclusion Criteria
• * Hospitalized patients (age ≥ 18 years) with high-risk AML defined as:
• • Patients with new diagnosis ≥ 60 years of age
• • An antecedent hematologic disorder
• • Therapy related-disease
• • Relapsed or primary refractory AML
• • Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial.
• • Caregiver Inclusion Criteria
• • Adult (≥18 years) relative or friend of a participating patient who the patient identifies as living with or has in-person contact with them at least twice per week.
• Exclusion Criteria:
• • - Patient Exclusion Criteria
• • Patients with a diagnosis of acute promyelocytic leukemia (APML)
• • Patients with AML receiving supportive care alone
• • Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits informed consent or compliance with study procedures
• • Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment
• • Patients expected to be discharged within 2 days