Investigational Use of Neuromuscular Ultrasound

Launched by NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE (NINDS) · Feb 11, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring the use of ultrasound, a technique that uses sound waves to create images, to better understand the health and function of nerves and muscles in people with various conditions like muscular dystrophy, peripheral neuropathy, and motor neuron disorders. The goal is to improve how we can observe and measure the function of these vital systems, which is important for diagnosing and treating nerve and muscle disorders.

To participate, you need to be an adult aged 18 or older. Healthy individuals are welcome, as well as those who have a neuromuscular disorder or show symptoms of one. Participants will attend up to five outpatient visits, where they will provide a medical history, undergo a physical exam, and have ultrasounds done on their nerves and muscles. The ultrasound involves applying gel to the skin and using a small probe that sends sound waves to create pictures. Some participants may also have nerve conduction studies, which involve placing small wires on the skin to measure how well nerves work. Overall, this study aims to gather important information while ensuring a comfortable and informative experience for participants.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• • 1. Healthy Volunteers-Adults
• • 1. Healthy adults, male or female, aged 18 years old or older,
• • 2. In good general health as evidenced by medical history, medical conditions under control such as hypertension acceptable.
• • 3. Stated willingness to comply with all study procedures and availability for the duration of the study.
• • 4. Ability of subject to understand and the willingness to sign a written informed consent document.
• • 2. Participants with neuromuscular disorders
• • 1. Adults, male or female, aged 18 years old or older,
• • 2. Diagnosed with a neuromuscular disorder or have signs and symptoms of nerve or muscle disorder or neuromuscular diaphragm dysfunction.
• • 3. Stated willingness to comply with all study procedures and availability for the duration of the study.
• • 4. Ability of subject to understand and the willingness to sign a written informed consent document.
• EXCLUSION CRITERIA:
• • 1. Healthy Volunteers-Adults
• • History of stroke, muscle disorders, peripheral neuropathy, or spine surgery
• • 2. Participants with neuromuscular disorders
• • No clinical evidence of a neuromuscular disorder on clinical evaluation.