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Search / Trial NCT05238181

Pyloric or Pseudopyloric Metaplasia of the Corpus Mucosa in Autoimmune Gastritis

Launched by NATIONAL CHENG-KUNG UNIVERSITY HOSPITAL · Feb 3, 2022

Trial Information

Current as of July 09, 2025

Enrolling by invitation

Keywords

Anemia, Pernicious Helicobacter Pylori Gastritis Metaplasia Intestinal Metaplasia Autoimmune Diseases

ClinConnect Summary

Autoimmune gastritis is not an uncommon disease among northern European ancestry, but its prevalence rates are unclear in other populations, including Taiwanese. A study showed that near 2% of persons more than 60 years old have undiagnosed pernicious anemia, one of the complications of autoimmune gastritis. Believed to be undiagnosed, patients are at risk of gastric malignancy and vitamin B12 deficiency-related complications until the end stage. Therefore, use of available diagnostic tools to diagnose patients with autoimmune gastritis has been important. However, autoimmune gastritis has ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients who present with relevant symptoms or signs of upper gastrointestinal diseases, including, but not limited to the following: impaired gastric emptying, epigastric discomfort, postprandial bloating, early satiety, epigastric pain, acid regurgitation, dyspepsia, anemia, or vitamin B12 deficiency, or iron deficiency, are candidates to be enrolled to receive gastroscopy.
  • Exclusion Criteria:
  • The exclusion criteria are as follows including use of aspirin, non-steroidal anti-inflammatory drugs, or cyclooxygenase-2 selective inhibitors for more than 3 months, or diagnosis with upper gastrointestinal cancer including esophagus, stomach, duodenum, mucosa-associated lymphoid tissue lymphoma, other gastric lymphoma, or pancreas.

About National Cheng Kung University Hospital

National Cheng Kung University Hospital is a leading academic medical institution in Taiwan, dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its extensive resources and expertise in various medical fields to facilitate groundbreaking studies that enhance patient care and medical knowledge. Committed to adhering to the highest ethical standards and regulatory guidelines, National Cheng Kung University Hospital fosters collaborations with researchers, healthcare professionals, and industry partners to drive the development of new therapies and improve health outcomes for diverse populations.

Locations

Tainan, , Taiwan

Patients applied

0 patients applied

Trial Officials

Hsiu-Chi Cheng, MD, PhD

Principal Investigator

National Cheng-Kung University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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