Invasive Decoding and Stimulation of Altered Reward Computations in Depression

Launched by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · Feb 4, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring new ways to treat major depressive disorder using advanced brain stimulation techniques. Researchers are specifically looking at areas of the brain that help control mood and decision-making. By studying brain activity in patients with epilepsy who are already receiving treatment, the team hopes to identify unusual brain responses related to depression. This information could help develop new treatments that stimulate the brain to improve mood and decision-making.

To participate in this study, you need to be an adult between 18 and 80 years old who is undergoing invasive monitoring for epilepsy. The study is currently recruiting participants, and both men and women are welcome. If you join, you can expect to have your brain activity monitored while you make choices, which will help researchers understand how depression affects brain function. This research could lead to innovative therapies for those struggling with depression.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - The study will follow clinical criteria for epilepsy patient recruitment for invasive monitoring. As a results, individuals of adults of all ages are expected to be included in this study.
• Exclusion Criteria:
• • Adults over 80 years of age will be excluded as per concerns of cognitive decline.
• • Children under 18 will be excluded from the study since the maturation of frontal lobes continues through adolescence and significant differences in frontal lobe functioning between children younger than 18 and adults are often observed.