Clinical Efficacy Evaluation of a Computer-aided Colonoscopy as Compared With the Standard Colonoscopy.

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Feb 13, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how effective a new technology called computer-aided detection (CADe) is during colonoscopy compared to the standard method. Colonoscopy is a procedure doctors use to look for and remove growths in the colon that could lead to colorectal cancer. This study aims to see if using CADe can help find more of these growths—called adenomas—than the traditional colonoscopy alone, which is important because finding and removing them can prevent cancer.

To participate in the trial, individuals must be scheduled for a colonoscopy to check for colorectal cancer or to monitor after a previous procedure. Eligible participants must also provide consent and agree that any findings will be treated right away. However, certain people, such as those with specific medical conditions or previous surgeries, are not eligible to join. If you choose to participate, you'll be part of a study that could help improve how colonoscopies are performed and potentially increase the number of adenomas found, making the procedure even more effective in preventing cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects who have given signed informed consent form
• • Informed consensus has been obtained that endoscopic resection should be performed if a lesion is found
• • Subjects who are scheduled for screening or diagnostic colonoscopy for colorectal cancer (CRC) or surveillance colonoscopy for post-polypectomy follow-up
• Exclusion Criteria:
• * Subjects with any of the following prior history or current conditions:
• • 1. Contraindications to colonoscopy
• • 2. Inflammatory bowel disease (IBD)
• • 3. Colorectal cancer (CRC)
• • 4. Familial adenomatous polyposis (FAP)
• • 5. Colonic stenosis
• • 6. Severe organ failure (cirrhosis of Child C, heart failure of ACC / AHA stage D)
• • 7. Active gastrointestinal (GI) Bleeding
• • 8. Pregnancy
• • 9. Prior colorectal surgery, including colonic or rectal resection (except for appendectomy, surgery on the anus, and polypectomy)
• • 10. Undergo colonoscopy within 3 years
• * Subjects with any of the following conditions per the investigator's judgement:
• • 1. High suspicion of IBD, CRC, and FAP.
• • 2. High risk of bleeding after endoscopic treatment, and difficult management of anticoagulation or antiplatelet medication.