Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure

Launched by NYU LANGONE HEALTH · Feb 13, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how a specific monitoring system can help doctors understand the fluid levels in patients with acute heart failure. When patients with heart failure are admitted to the hospital, they may need diuretics, which are medications that help remove excess fluid from the body. The trial will involve 50 patients who will be closely monitored using a non-invasive device called the Starling Fluid Management System. This system helps track heart function and fluid status, which can guide treatment decisions.

To participate in this study, patients need to have a diagnosis of acute heart failure that requires treatment with intravenous diuretics and must be admitted to a specialized cardiac care unit. They also need to be able to give their consent to participate. Patients who are pregnant, under 18, or have certain medical conditions may not be eligible. Those who join the trial can expect regular monitoring and support from the healthcare team as part of their care. This research aims to improve the management of heart failure and ensure that patients receive the best possible treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Diagnosis of congestive acute decompensated heart failure (preserved or reduced ejection fraction) requiring clinically indicated IV diuresis
• • 2. Admission to coronary/cardiac intensive care unit or cardiac step down unit
• • 3. Able to provide written informed consent
• • 4. Anticipated need for IV diuretics \> 24 hrs
• Exclusion Criteria:
• • 1. Prisoner, pregnancy or post-partum stage, or age \< 18 years
• • 2. Known allergy to sensory material or gel
• • 3. End stage renal disease or need for CRRT
• • 4. Inability or contraindication to do a passive leg raise with both extremities (i.e., balloon pump, impella, spinal injury, amputation)
• • 5. Other situation that might increase subject risk, interfere with study procedures, or confound study findings based on the opinion of the clinician/investigator
• • 6. Inability to provide informed consent