REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI

Launched by MCMASTER UNIVERSITY · Feb 16, 2022

Keywords

ClinConnect Summary

The REVIVe trial is studying how frailty, which means having reduced strength and health, affects the chances of survival and recovery in adults and children who have become critically ill due to COVID-19 or other serious respiratory infections. Researchers want to learn if patients with frailty have a harder time surviving their illness and if they experience more health issues afterward compared to those who are not frail. They will also look at the types of rehabilitation, or recovery programs, that these patients receive to help improve their health and quality of life after their time in the Intensive Care Unit (ICU).

To participate in this study, individuals must be adults or children who have been admitted to the ICU with COVID-19 or acute respiratory infections and require special breathing support. The study is currently recruiting participants from various ICUs. Those who join will have their health and recovery tracked, helping researchers understand the best ways to support survivors and plan for their care after leaving the hospital. This research is important because it aims to improve outcomes for those affected by COVID-19 and respiratory illnesses, helping survivors regain their strength and overall well-being.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult and pediatric survivors of COVID-19 or acute respiratory infection admitted to participating intensive care units (ICUs) and PICUs. The investigators define children as less than, and adults as greater than or equal to, 18 years old, respectively. The investigators will include adults and pediatrics with a confirmed diagnosis of COVID-19, pediatric patients with MIS-C, and adults and pediatrics with suspected or proven acute respiratory infection with onset within 14 days of ICU/PICU admission and requiring invasive mechanical ventilation, non-invasive ventilation, or high flow oxygen therapy.
• Exclusion Criteria:
• • Patients who were admitted to ICU for \<24 hours