Metabolic Profiling of Hematopoietic Stem Cells in Clonal Hematopoiesis (CHIP)

Launched by IMELDA HOSPITAL, BONHEIDEN · Feb 10, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how certain changes in blood cells, known as clonal hematopoiesis, might affect bone health as people age. Researchers will collect bone marrow samples from patients who are having hip surgery, and they will analyze these samples to understand how the cells function and any genetic changes that may be present. The goal is to learn more about how these changes could be linked to conditions like osteoporosis and osteoarthritis.

To participate in this study, you must be 65 years old or older and not have any known blood disorders like leukemia or cancer. If you join the trial, you will provide blood and bone marrow samples, which will help researchers study how your cells are functioning. It's important to note that participants will need to give their consent to be part of the study. This research could lead to better understanding and treatments for age-related bone issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 65 years and older
• Exclusion Criteria:
• • known haematological condition (myelodysplasia, leukemia, cancer)
• • inability to provide written informed consent