Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients

Launched by RWTH AACHEN UNIVERSITY · Feb 9, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how different older adults react to medications, especially those who take multiple drugs at the same time, a situation known as polypharmacy. The goal is to create a better understanding of which patients may be more vulnerable to side effects from their medications. By looking at factors like genetics, the researchers hope to identify individual risk profiles for drug-related problems in older patients.

To be eligible for this study, participants need to be 70 years or older and currently taking three or more medications. They should also be patients at a specific outpatient clinic that focuses on helping older adults manage their medications. Participants will need to be able to move at least in a wheelchair and provide consent to join the study, either themselves or through a legal representative. Since the trial is not yet recruiting, there's no need to worry about immediate participation, but it’s important to know that those who cannot communicate effectively or are considered terminally ill will not be included. If you decide to participate, you can expect to contribute to valuable research that may improve medication safety for older adults in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 70 years or older
• • Current drug therapy with three or more drugs
• • Being a patient in the interdisciplinary polypharmacy consultation service of the geriatric university outpatient clinic
• • Sufficient mobility (minimum: Wheelchair mobility)
• • Written informed consent of the patient or the legal representative
• Exclusion Criteria:
• • No sufficient communication possible
• • Patients classified as terminally ill by the medical staff
• • Patients, that are incapable to give their informed consent and who do not have a legal representative