Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy
Launched by KAROLINSKA INSTITUTET · Feb 9, 2022
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying two different types of cognitive-behavioral therapy (CBT) to see which is more effective for treating anxiety disorders, such as panic disorder, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, and posttraumatic stress disorder. One type of therapy focuses on specific diagnoses, while the other is designed to address symptoms across different anxiety disorders. The goal of this pilot study is to determine if it is possible to conduct a larger trial and to see how well patients respond to each type of therapy in routine outpatient care in Stockholm, Sweden.
To participate in this study, individuals must be between 18 and 65 years old, able to speak Swedish, and have a main diagnosis of one of the specified anxiety disorders. They should also be on stable medication for at least six weeks before starting the treatment. Participants can expect to receive therapy tailored to their needs, and the study aims to ensure that they feel comfortable and supported throughout the process. It’s important to note that individuals with certain other mental health issues or severe risks, such as suicidal thoughts, cannot take part in the trial.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 18-65 years of age,
- • Being able to speak Swedish without interpreter support,
- • A principal diagnosis of panic disorder, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, or posttraumatic stress disorder, and
- • Pharmacological treatment (if any) that is stable six weeks prior to treatment start
- Exclusion Criteria:
- • Current diagnosis of psychotic disorder, bipolar disorder, or moderate to severe substance use disorder,
- • Moderate to severe risk of suicide,
- • Psychiatric, somatic, or social problems which require other management or intervention than cognitive-behavioral therapy, and
- • Other simultaneous psychological treatment
About Karolinska Institutet
Karolinska Institutet is a renowned medical university located in Sweden, recognized for its commitment to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the institution focuses on translating scientific discoveries into effective treatments and therapies, emphasizing patient-centered approaches. With a strong emphasis on collaboration and interdisciplinary research, Karolinska Institutet plays a pivotal role in addressing global health challenges and improving patient outcomes, leveraging its extensive network of experts and state-of-the-art facilities to drive clinical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stockholm, , Sweden
Patients applied
Trial Officials
Benjamin Bohman, PhD
Principal Investigator
Karolinska Institutet
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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