Infective Endocarditis Surgery Using Conventional Prosthetic Valves Versus Cryopreserved Aortic Homograft

Launched by CENTRE CARDIOLOGIQUE DU NORD · Feb 14, 2022

Keywords

ClinConnect Summary

The target population enrolled in the study includes patients with aortic-valve endocarditis at risk of embolization, heart failure and uncontrolled infection undergoing AVR with the use of CAH or conventional mechanical or stent xenograft valve prostheses. Individuals were adequately treated per applicable standards, including for the treatment of infection, LV dysfunction and heart failure. Patients enrolled in the studies were NYHA functional class II, III, or outpatient NYHA IV.

Three groups of patients are included in the study. Patients who were managed with CAH, patients who receive...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Duke Criteria
• • Uncontrolled Infection Local abscess Large vegetation False aneurysm, Fistula, Dehiscence of PV
• • Embolism Large vegetation \>10mm, persistent infection
• • Heart Failure Involvement of aortic root, intervalvular fibrosa, pulmonary edema, cardiogenic shock
• Exclusion Criteria :
• • Pediatric
• • Any echocardiographic evidence of absence of IE