Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia

Launched by UNIVERSITY OF MISSOURI-COLUMBIA · Feb 24, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how men and women respond differently to low oxygen levels (known as hypoxia) and how this affects blood vessel function. The goal is to understand these differences better, as they may help improve treatments for conditions related to blood flow and oxygen supply. The trial is currently looking for healthy adults aged 18 to 45 who are within a normal weight range and do not smoke or use drugs. Women who are pregnant or breastfeeding cannot participate.

If you decide to take part in this study, you will undergo some tests to see how your body reacts to low oxygen levels. It’s important to note that certain health conditions, like high blood pressure, diabetes, or any major diseases affecting your heart, lungs, or nervous system, would prevent you from joining. Participants will contribute to valuable research that could lead to better understanding and treatments for various health issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • healthy adult men and women;
• • 18-45 years of age;
• • BMI 18-30 kg/m2;
• • non-pregnant/non-breastfeeding;
• • non-nicotine users;
• Exclusion Criteria:
• • Pregnancy, breastfeeding, hormonal contraceptives
• • Diagnosed sleep apnea
• • Current smoking/Nicotine use/drug use
• • Nerve/neurologic disease
• • Cardiovascular, hepatic, renal, respiratory disease
• • Blood pressure ≥140/90 mmHg
• • Diabetes, Polycystic ovarian syndrome
• • Communication barriers
• • Prescription medications
• • Recent COVID-19 diagnosis with symptoms