Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

Launched by EMORY UNIVERSITY · Feb 16, 2022

Keywords

ClinConnect Summary

This clinical trial is studying two different medications, sugammadex and neostigmine, to help reverse the effects of anesthesia in children who are having surgery for appendicitis. The goal is to see which medication works better in helping kids wake up from anesthesia after a laparoscopic appendectomy, which is a type of surgery to remove the appendix. The trial is being conducted at Children's Healthcare of Atlanta - Egleston and is currently recruiting participants.

To be eligible for this study, children aged 2 to 17 years who have been diagnosed with acute appendicitis and are set to have this surgery can join. Parents or guardians will need to provide informed consent, meaning they will agree to participate after understanding the details of the study. However, children with allergies to either medication or those with certain medical conditions, like kidney problems, cannot participate. If your child takes part in this study, they will receive one of the two medications to help reverse anesthesia, and the doctors will monitor their recovery closely.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients 2-17 years of age
• • Diagnosis of acute appendicitis
• • Patient undergoing laparoscopic appendectomy at Children's Healthcare of Atlanta- Egleston.
• • Parent or Legal Authorized Representative willing to participate, able to understand and sign an informed consent
• Exclusion Criteria:
• • Patient with an allergy to Sugammadex or Neostigmine
• • History of renal dysfunction
• • Parent or legal guardian unwilling or unable or unable to understand the informed consent