Study on the Significance of Auricular Clip in Prevention and Treatment of Valvular Heart Disease Atrial Thrombosis

Launched by SECOND AFFILIATED HOSPITAL OF NANCHANG UNIVERSITY · Feb 20, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at a special device called an auricular clip to see if it can help prevent blood clots in patients with valvular heart disease, particularly those who have a condition known as atrial fibrillation. Blood clots can lead to serious problems like strokes, so finding effective ways to prevent them is very important. The trial aims to evaluate how safe and effective this device is in treating and preventing these clots, and it will also help improve future treatment strategies for patients.

To participate in this study, you need to be between 18 and 75 years old and have been diagnosed with valvular heart disease, which affects how your heart valves work. You should also have a specific level of heart function that is manageable for surgery. If you’ve had certain previous heart surgeries or other conditions that might make it unsafe for you to participate, you may not be eligible. If you join the trial, you can expect to receive detailed information about your treatment and follow-up care, and you’ll need to agree to participate fully in the study. This could be a valuable opportunity to contribute to research that aims to improve heart health for many patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with valvular heart disease aged between 18 and 75
• • 2. Valvular heart disease \[Cardiovascular Surgery Volume, Clinical Diagnosis and Treatment Guidelines, Chinese Medical Association (2011 edition)\]
• • 3. Preoperative cardiac function grade II-III (NYHA), no operation-related contraindications
• • 4. Understand the nature of this study, agree to participate in all terms of this study, sign informed consent, agree to accept postoperative treatment plan and follow-up requirements, and cooperate to complete follow-up
• Exclusion Criteria:
• • 1. Patients whose left atrial appendage has been resected or occluded
• • 2. She had a history of open heart surgery with extensive adhesion of the pericardium
• • 3. Patients cannot be returned due to other reasons
• • 4. Failed to reach the end point in clinical trials of other drugs or devices
• • 5. X-ray is contraindicated or not suitable for TEE examination
• • 6. Those who are considered unsuitable for the clinical trial by the investigator